Evidence map›Paper›PMID 31952531›Full record

ArticleBMC veterinary research2020

Temporal and anatomical distribution of

Taesik Yun, Wonguk Lee, Ji-Houn Kang, Mhan-Pyo Yang, Byeong-Teck Kang

Abstract read
In one paragraph

Article in BMC veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Taesik YunVeterinary Teaching Hospital, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea.
Wonguk LeeDepartment of Nuclear Medicine, Chungbuk National University Hospital, Cheongju, Chungbuk, 28644, South Korea.
Ji-Houn KangVeterinary Teaching Hospital, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea.
Mhan-Pyo YangVeterinary Teaching Hospital, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea.
Byeong-Teck KangVeterinary Teaching Hospital, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, 28644, South Korea. kangbt@chungbuk.ac.kr.ORCID http://orcid.org/0000-0002-4471-4342

Funding

Cooperative Research Program for Agriculture Science and Technology Development PJ01283408Ministry of Education 2017R1D1A3B03028863
6 · The paper itself

Abstract

backgroundPositron emission tomography (PET) is increasingly being used as an imaging modality for clinical and research applications in veterinary medicine. Amyloid PET has become a useful tool for diagnosing Alzheimer's disease (AD) in humans, by accurately identifying amyloid-beta (Aβ) plaques. Cognitive dysfunction syndrome in dogs shows cognitive and pathophysiologic characteristics similar to AD. Therefore, we assessed the physiologic characteristics of uptake of

resultsAmong the six cerebral cortical regions, the cingulate cortices and frontal lobe showed the highest SUVRs. The lowest SUVR was observed in the occipital lobe. The average values of the cortical SUVRs were 1.25, 1.26, and 1.27 at 30, 60, and 90 min post-injection, respectively. Tracer uptake on dynamic scans was rapid, peaking within 4 min post-injection. After reaching this early maximum, cerebral cortical regions showed a curve with a steep descent, whereas cerebral white matter demonstrated a curve with a slow decline, resulting in a large gap between cerebral cortical regions and white matter.

conclusionThis study provides normal baseline data of

Indexed as

Aniline CompoundsBenzothiazolesDogsAmyloidAnimalsBrainCognitive DysfunctionDog DiseasesFemaleFluorine RadioisotopesMalePositron-Emission TomographyAmyloidAniline CompoundsBenzothiazolesFluorine Radioisotopesflutemetamol18F-flutemetamolAmyloidCognitive dysfunction syndromeDogPositron emission tomography

Identifiers

PMID31952531
PMCPMC6969467

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.