Evidence map›Paper›PMID 31952464›Full record

ArticleThyroid : official journal of the American Thyroid Association2020

Generation of Novel Genetic Models to Dissect Resistance to Thyroid Hormone Receptor α in Zebrafish.

Cho Rong Han, Erik Holmsen, Blake Carrington, Kevin Bishop, Yuelin Jack Zhu, Matthew Starost, Paul Meltzer, Raman Sood, Paul Liu, Sheue-Yann Cheng

Open access · greenAbstract read
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  9. Review
  10. Thyroid Hormone Receptor α Mutations Cause Heart Defects in Zebrafish.Thyroid : official journal of the American Thyroid Association · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Cho Rong HanLaboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Erik HolmsenLaboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Blake CarringtonZebrafish Core, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Kevin BishopZebrafish Core, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Yuelin Jack ZhuLaboratory of Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Matthew StarostDivision of Veterinary Resources, Diagnostic and Research Services Branch, National Institutes of Health, Bethesda, Maryland.
Paul MeltzerLaboratory of Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
Raman SoodZebrafish Core, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Paul LiuZebrafish Core, Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.
Sheue-Yann ChengLaboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
National Institutes of Health · USOffice of Research Services · US

Funding

Cancer Genomics Technology DevelopmentZIABC011091 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI MELTZER, PAUL S. · 2009 to 2025
$16.9M
Thyroid Hormone Receptors in Health and DiseaseZIABC008752 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHENG, SHEUE-YANN · 2009 to 2025
$12.9M
NHGRI/DIR Zebrafish CoreZICHG200351 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI SOOD, RAMAN · 2015 to 2025
$12.1M
Laboratory of Genitourinary Cancer Pathogenesis Microscopy Core FacilityZICBC010947 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LAKE, ROSS · 2009 to 2025
$11.0M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAnimals, Genetically ModifiedDisease Models, AnimalGenes, erbAGrowth DisordersGrowth HormoneInsulin-Like Growth Factor IThyroid Hormone Receptors alphaThyroid Hormone Resistance SyndromeZebrafishGrowth HormoneInsulin-Like Growth Factor IThyroid Hormone Receptors alphaepidermis hypoplasiagrowth retardationpituitary defectsRNA-seqTRα mutationszebrafish

Identifiers

PMID31952464
PMCPMC7047097
OpenAlexW3000376701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.