Evidence map›Paper›PMID 31952244›Full record

ReviewMolecules (Basel, Switzerland)2020

Continuous Flow Photochemistry for the Preparation of Bioactive Molecules.

Mara Di Filippo, Cormac Bracken, Marcus Baumann

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Solid-State Photochemistry in Resonant Acoustic Mixers.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Synthesis of substituted 8Beilstein journal of organic chemistry · 2023
    Article
  8. Review
  9. Review
  10. High Yielding Continuous-Flow Synthesis of Norketamine.Organic process research & development · 2022
    Review
  11. Review
  12. Article
  13. Continuous Flow Synthesis of Anticancer Drugs.Molecules (Basel, Switzerland) · 2021
    Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mara Di FilippoSchool of Chemistry, University College Dublin, Science Centre South, Belfield, Dublin 4, Ireland.
Cormac BrackenSchool of Chemistry, University College Dublin, Science Centre South, Belfield, Dublin 4, Ireland.
Marcus BaumannSchool of Chemistry, University College Dublin, Science Centre South, Belfield, Dublin 4, Ireland.ORCID 0000-0002-6996-5893

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The last decade has witnessed a remarkable development towards improved and new photochemical transformations in response to greener and more sustainable chemical synthesis needs. Additionally, the availability of modern continuous flow reactors has enabled widespread applications in view of more streamlined and custom designed flow processes. In this focused review article, we wish to evaluate the standing of the field of continuous flow photochemistry with a specific emphasis on the generation of bioactive entities, including natural products, drugs and their precursors. To this end we highlight key developments in this field that have contributed to the progress achieved to date. Dedicated sections present the variety of suitable reactor designs and set-ups available; a short discussion on the relevance of greener and more sustainable approaches; and selected key applications in the area of bioactive structures. A final section outlines remaining challenges and areas that will benefit from further developments in this fast-moving area. It is hoped that this report provides a valuable update on this important field of synthetic chemistry which may fuel developments in the future.

Indexed as

Photochemical ProcessesBiological ProductsHumansPhotochemistryBiological Productsbioactive moleculescontinuous flow chemistryenabling technologiesmedicinal chemistryphotocatalysisphotochemistryprocess development

Identifiers

PMID31952244
PMCPMC7024297

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.