Evidence map›Paper›PMID 31952221›Full record

ArticleCells2020

Adrián Montaño, Jose Luis Ordoñez, Verónica Alonso-Pérez, Jesús Hernández-Sánchez, Sandra Santos, Teresa González, Rocío Benito, Ignacio García-Tuñón, Jesús María Hernández-Rivas

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Adrián MontañoIBSAL, IBMCC, Cancer Research Center, Universidad de Salamanca-CSIC, 37007 Salamanca, Spain.
Jose Luis OrdoñezIBSAL, IBMCC, Cancer Research Center, Universidad de Salamanca-CSIC, 37007 Salamanca, Spain.
Verónica Alonso-PérezIBSAL, IBMCC, Cancer Research Center, Universidad de Salamanca-CSIC, 37007 Salamanca, Spain.
Jesús Hernández-SánchezIBSAL, IBMCC, Cancer Research Center, Universidad de Salamanca-CSIC, 37007 Salamanca, Spain.
Sandra SantosIBSAL, IBMCC, Cancer Research Center, Universidad de Salamanca-CSIC, 37007 Salamanca, Spain.
Teresa GonzálezIBSAL, IBMCC, Cancer Research Center, Universidad de Salamanca-CSIC, 37007 Salamanca, Spain.
Rocío BenitoIBSAL, IBMCC, Cancer Research Center, Universidad de Salamanca-CSIC, 37007 Salamanca, Spain.
Ignacio García-TuñónIBSAL, IBMCC, Cancer Research Center, Universidad de Salamanca-CSIC, 37007 Salamanca, Spain.
Jesús María Hernández-RivasIBSAL, IBMCC, Cancer Research Center, Universidad de Salamanca-CSIC, 37007 Salamanca, Spain.
Universidad de Salamanca · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe t(12;21)(p13;q22), which fuses

methodsGeneration of an

resultsThe expression of

conclusionsETV6/RUNX1 fusion protein seems to play an important role in the maintenance of the leukemic phenotype and could thus become a potential therapeutic target.

Indexed as

Models, BiologicalCell ProliferationCore Binding Factor Alpha 2 SubunitCRISPR-Associated Protein 9ETS Translocation Variant 6 ProteinGene EditingHumansPrecursor Cell Lymphoblastic Leukemia-LymphomaProto-Oncogene Proteins c-etsRepressor ProteinsTumor Cells, CulturedCore Binding Factor Alpha 2 SubunitCRISPR-Associated Protein 9ETS Translocation Variant 6 ProteinProto-Oncogene Proteins c-etsRepressor ProteinsRUNX1 protein, humanacute lymphoblastic leukaemiaCRISPR/Cas9ETV6/RUNX1genome edition

Identifiers

PMID31952221
PMCPMC7017301
OpenAlexW3000731800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.