Evidence map›Paper›PMID 31952203›Full record

ArticleMarine drugs2020

Complex Polysaccharide-Based Nanocomposites for Oral Insulin Delivery.

Mar Collado-González, M Cristina Ferreri, Alessandra R Freitas, Ana Cláudia Santos, Nuno R Ferreira, Guzmán Carissimi, Joana A D Sequeira, F Guillermo Díaz Baños, Gloria Villora, Francisco Veiga and 1 more

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Mar Collado-GonzálezDepartment of Food Science and Nutrition, University of Leeds, Leeds LS2 9JT, UK.
M Cristina FerreriDepartment of Pharmaceutical technology, Faculty of Pharmacy of the University of Coimbra, 3000-548 Coimbra, Portugal.
Alessandra R FreitasDepartment of Pharmaceutical technology, Faculty of Pharmacy of the University of Coimbra, 3000-548 Coimbra, Portugal.
Ana Cláudia SantosDepartment of Pharmaceutical technology, Faculty of Pharmacy of the University of Coimbra, 3000-548 Coimbra, Portugal.
Nuno R FerreiraFaculty of Pharmacy of the University of Coimbra, 3000-548 Coimbra, Portugal.
Guzmán CarissimiDepartment of Chemical Engineering, University of Murcia, 30100 Murcia, Spain.
Joana A D SequeiraDepartment of Pharmaceutical technology, Faculty of Pharmacy of the University of Coimbra, 3000-548 Coimbra, Portugal.
F Guillermo Díaz BañosDepartment of Physical Chemistry, University of Murcia, 30100 Murcia, Spain.
Gloria VilloraDepartment of Chemical Engineering, University of Murcia, 30100 Murcia, Spain.
Francisco VeigaDepartment of Pharmaceutical technology, Faculty of Pharmacy of the University of Coimbra, 3000-548 Coimbra, Portugal.
Antonio RibeiroDepartment of Pharmaceutical technology, Faculty of Pharmacy of the University of Coimbra, 3000-548 Coimbra, Portugal.
University of Coimbra · PTUniversidad de Murcia · ESRede de Química e Tecnologia · PTUniversity of Leeds · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polyelectrolyte nanocomposites rarely reach a stable state and aggregation often occurs. Here, we report the synthesis of nanocomposites for the oral delivery of insulin composed of alginate, dextran sulfate, poly-(ethylene glycol) 4000, poloxamer 188, chitosan, and bovine serum albumin. The nanocomposites were obtained by Ca

Indexed as

Administration, OralAlginatesChitosanDrug CarriersDrug Delivery SystemsGelsInsulinNanocompositesPolyethylene GlycolsPolysaccharidesSerum Albumin, BovineStatic ElectricityAlginatesChitosanDrug CarriersGelsInsulinpolyethylene glycol 4000Polyethylene GlycolsPolysaccharidesSerum Albumin, Bovinealginate polysaccharide nanocompositechitosanLUMiSizerstability

Identifiers

PMID31952203
PMCPMC7024366
OpenAlexW2999456778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.