Evidence map›Paper›PMID 31952120›Full record

ArticleJournal of clinical medicine2020

Assessment of the Minimal Targeted Biopsy Core Number per MRI Lesion for Improving Prostate Cancer Grading Prediction.

Guillaume Ploussard, Jean-Baptiste Beauval, Raphaële Renard-Penna, Marine Lesourd, Cécile Manceau, Christophe Almeras, Jean-Romain Gautier, Guillaume Loison, Daniel Portalez, Ambroise Salin and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Guillaume PloussardDepartment of Urology, La Croix du Sud Hospital, 52, chemin de Ribaute, 31130 Quint Fonsegrives, France.
Jean-Baptiste BeauvalDepartment of Urology, La Croix du Sud Hospital, 52, chemin de Ribaute, 31130 Quint Fonsegrives, France.
Raphaële Renard-PennaDepartment of Radiology, CHU La Pitié Salpétrière/Tenon, Sorbonne Université, 75005 Paris, France.
Marine LesourdDepartment of Urology, Institut Universitaire du Cancer Toulouse-Oncopole, 31000 Toulouse, France.ORCID 0000-0001-6001-1391
Cécile ManceauDepartment of Urology, CHU Toulouse, 31000 Toulouse, France.ORCID 0000-0003-1597-4767
Christophe AlmerasDepartment of Urology, La Croix du Sud Hospital, 52, chemin de Ribaute, 31130 Quint Fonsegrives, France.ORCID 0000-0002-1658-9177
Jean-Romain GautierDepartment of Urology, La Croix du Sud Hospital, 52, chemin de Ribaute, 31130 Quint Fonsegrives, France.
Guillaume LoisonDepartment of Urology, La Croix du Sud Hospital, 52, chemin de Ribaute, 31130 Quint Fonsegrives, France.
Daniel PortalezDepartment of Radiology, Institut Universitaire du Cancer Toulouse-Oncopole, 31000 Toulouse, France.
Ambroise SalinDepartment of Urology, La Croix du Sud Hospital, 52, chemin de Ribaute, 31130 Quint Fonsegrives, France.
Michel SouliéDepartment of Urology, CHU Toulouse, 31000 Toulouse, France.
Christophe TollonDepartment of Urology, La Croix du Sud Hospital, 52, chemin de Ribaute, 31130 Quint Fonsegrives, France.
Bernard MalavaudDepartment of Urology, Institut Universitaire du Cancer Toulouse-Oncopole, 31000 Toulouse, France.
Mathieu RoumiguiéDepartment of Urology, Institut Universitaire du Cancer Toulouse-Oncopole, 31000 Toulouse, France.
Lyon Genou Centre Albert Trillat · FRCentre Hospitalier Universitaire de Toulouse · FRInstitut universitaire du cancer de Toulouse Oncopole · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo study the impact of MRI characteristics and of targeted biopsy (TB) core number on the final grade group (GG) prediction. MATERIALS AND

methodsThe cohort was 478 consecutive patients who underwent radical prostatectomy (RP) after positive mpMRI (multiparametric magnetic resonance imaging) followed by fusion TB. Endpoints were the upgrading and concordance rates between TB and RP specimens.

resultsUpgrading rate after TB was 40.6%. Patients with upgrading had lower PIRADS (Prostate Imaging-Reporting and Data System) scores (

conclusionsGrade group prediction by TB is significantly improved by higher PIRADS score, larger lesion size, and increased TB per lesion. At least four TB cores should be taken in PIRADS 3 score lesions, whereas three cores seem enough in PIRADS 4-5 cases to improve GG prediction and limit upgrading risk.

Indexed as

biopsyfusion biopsiesMRIprostate cancerradical prostatectomysystematic biopsiestargeted biopsiesupgrading

Identifiers

PMID31952120
PMCPMC7019328
OpenAlexW2999195129

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.