ArticleCell host & microbe2020
JAK-ing into M1/M2 Polarization SteErs Salmonella-Containing Macrophages Away from Immune Attack to Promote Bacterial Persistence.
Article in Cell host & microbe, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Review
- Disruption of sulfur transferase complex increases bacterial intramacrophage persistence.PLoS pathogens · 2025Article
- Single-cell RNA sequencing of the spleen reveals differences in Salmonella typhimurium infection mechanisms between different chicken breeds.Poultry science · 2025Article
- Infection biology ofEcoSal Plus · 2024Review
- Streptococcal arginine deiminase system defences macrophage bactericidal effect mediated by XRE family protein XtrSs.Virulence · 2024Article
- Macrophage fate: to kill or not to kill?Infection and immunity · 2024Review
- Emerging Strategies against Non-TyphoidalCurrent issues in molecular biology · 2024Review
- Mitochondrial electron transport chain in macrophage reprogramming: Potential role in antibacterial immune response.Current research in immunology · 2024Review
- Strategies adopted by Salmonella to survive in host: a review.Archives of microbiology · 2023Review
- SteE Enhances the Virulence ofFrontiers in veterinary science · 2022Article
- Resolving macrophage polarization through distinct CaiScience · 2021Article
- A Proteomic Atlas of Lineage and Cancer-Polarized Expression Modules in Myeloid Cells Modeling Immunosuppressive Tumor-Infiltrating Subsets.Journal of personalized medicine · 2021Article
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite decades of study, the molecular basis for granuloma formation and restriction of chronic pathogens remains murky. Three articles reveal how Salmonella rewires macrophage polarization (Panagi et al. and Gibbs et al.) to shift the balance between M1 and M2 granuloma macrophages and resist TNF-mediated clearance (Pham et al.).
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Identifiers
31951822What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.