ArticleAACN advanced critical care2019
Opioid and Benzodiazepine Iatrogenic Withdrawal Syndrome in Patients in the Intensive Care Unit.
Article in AACN advanced critical care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Iatrogenic withdrawal syndrome in adult intensive care unit: a scoping review.Frontiers in medicine · 2025Pooled it
- Usability and Quality of UCISAB, a Clinical Decision Support System for Optimization of Analgesia and Sedation Infusions in the ICU: A Multicenter, Cross-Sectional, Mixed-Methods Usability Evaluation in Colombia.Journal of clinical medicine · 2026Article
- Recognising and differentiating paroxysmal sympathetic hyperactivity after severe traumatic brain injury: a practical diagnostic approach.Acta neurologica Belgica · 2026Review
- Characterizing the Relationship Between Nonmedical Use of Gabapentin and Gabapentin Prescribing Among Individuals With Opioid Use Disorder.Journal of addiction medicine · 2026Article
- Low-Dose Buprenorphine Initiations During Opioid and Sedative Weaning in Mechanically Ventilated Neurocritical Care Patients: A Retrospective Pilot Cohort Study.Neurocritical care · 2026Article
- Sedation and analgesia strategies in the neuro intensive care unit.World journal of critical care medicine · 2025Review
- Use of dexmedetomidine during mechanical ventilation in extremely preterm and extremely low birth weight neonates receiving morphine: A single-center retrospective study.Paediatric & neonatal pain · 2024Article
- Prevalence and correlates of DSM-5 opioid withdrawal syndrome in U.S. adults with non-medical use of prescription opioids: results from a national sample.The American journal of drug and alcohol abuse · 2023Article
- Perioperative Anxiety and Depression in Older Adults: Epidemiology and Treatment.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023Review
- Opioid, sedative, preadmission medication and iatrogenic withdrawal risk in UK adult critically ill patients: a point prevalence study.International journal of clinical pharmacy · 2023Article
- Modified ABCDEF-Bundles for Critically Ill Pediatric Patients - What Could They Look Like?Frontiers in pediatrics · 2022Review
- Escalation to Barbiturate-Induced Coma for Refractory Seizures after Liver Transplantation.Case reports in hepatology · 2022Article
- How to Manage Withdrawal of Sedation and Analgesia in Mechanically Ventilated COVID-19 Patients?Journal of clinical medicine · 2021Review
- Incidence patterns of nervous system diseases after carbon monoxide poisoning: a retrospective longitudinal study in South Korea from 2012 to 2018.Clinical and experimental emergency medicine · 2021Article
- Analgesia and sedation in patients with ARDS.Intensive care medicine · 2020Review
- Clinical Utility of the Behavioral Pain Assessment Tool in Patients Admitted in the Intensive Care Unit.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Iatrogenic withdrawal syndrome is an increasingly recognized issue among adult patients in the intensive care unit. The prolonged use of opioids and benzodiazepines during the intensive care unit stay and preexisting disorders associated with their use put patients at risk of developing iatrogenic withdrawal syndrome. Although research to date is scant regarding iatrogenic withdrawal syndrome in adult patients in the intensive care unit, it is important to recognize and adequately manage iatrogenic withdrawal syndrome in order to prevent possible negative outcomes during and after a patient's intensive care unit stay. This article discusses in depth 8 studies of iatrogenic withdrawal syndrome among adult patients in the intensive care unit. It also addresses important aspects of opioid and benzodiazepine iatrogenic withdrawal syndrome, including prevalence, risk factors, and assessment and considers its prevention and management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.