Evidence map›Paper›PMID 31951563›Full record

ArticleStem cell reports2019

New Drugs for an Old Foe: Mycobacterium tuberculosis Meets PSC-Derived Macrophages.

Kathrin Haake, Nico Lachmann

Abstract read
In one paragraph

Article in Stem cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kathrin HaakeInstitute of Experimental Hematology, RG Translational Hematology of Congenital Diseases, Hannover Medical School, Hannover, Germany; REBIRTH - Research Center for Translational and Regenerative Medicine, Hannover Medical School, Hannover, Germany.
Nico LachmannInstitute of Experimental Hematology, RG Translational Hematology of Congenital Diseases, Hannover Medical School, Hannover, Germany; REBIRTH - Research Center for Translational and Regenerative Medicine, Hannover Medical School, Hannover, Germany. Electronic address: lachmann.nico@mh-hannover.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections with Mycobacterium tuberculosis (Mtb) are still among the top 10 causes of death worldwide, highlighting the utmost need for new forms of medical treatments. In this issue of Stem Cell Reports, Han et al. (2019) describe a technique to screen therapeutically active compounds targeting Mtb using pluripotent stem cell-derived macrophages.

Indexed as

Drug DiscoveryAntitubercular AgentsCell DifferentiationHumansInduced Pluripotent Stem CellsMacrophagesMycobacterium tuberculosisPluripotent Stem CellsAntitubercular Agents

Identifiers

PMID31951563
PMCPMC6915800

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.