Evidence map›Paper›PMID 31951536›Full record

ArticleStructure (London, England : 1993)2020

Getting Close: Insight into the Structure and Function of K11/K48-Branched Ubiquitin Chains.

Regina Baur, Michael Rape

Abstract readComment
PubMed Publisher
In one paragraph

Article in Structure (London, England : 1993), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
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  8. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Regina BaurHoward Hughes Medical Institute, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology at University of California, Berkeley, Berkeley, CA 94720, USA; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.
Michael RapeHoward Hughes Medical Institute, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology at University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: mrape@berkeley.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

K11/K48-branched ubiquitin chains are proteasomal priority signals that elicit the rapid elimination of mitotic regulators and aggregation-prone proteins. Indicative of an intriguing signaling mode, Boughton et al. (2019) unravel an interaction between distal subunits of K11/K48-branched ubiquitin trimers that could provide a combined surface for recognition by the proteasomal receptor RPN1.

Indexed as

Proteasome Endopeptidase ComplexUbiquitinCarrier ProteinsSignal TransductionUbiquitinationCarrier ProteinsProteasome Endopeptidase ComplexUbiquitin

Identifiers

PMID31951536

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.