Evidence map›Paper›PMID 31951412›Full record

ArticleThe journal of physical chemistry letters2020

In-Cell Trityl-Trityl Distance Measurements on Proteins.

Yin Yang, Bin-Bin Pan, Xiaoli Tan, Feng Yang, Yangping Liu, Xun-Cheng Su, Daniella Goldfarb

Open access · hybridAbstract read
In one paragraph

Article in The journal of physical chemistry letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Article
  3. Protein Modeling with DEER Spectroscopy.Annual review of biophysics · 2025
    Review
  4. Rapid Analysis of DEER Signals Including Short Distances.The journal of physical chemistry letters · 2025
    Article
  5. Endogenous Cu(II) Labeling for Distance Measurements on Proteins by EPR.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. A newJournal of magnetic resonance (San Diego, Calif. : 1997) · 2023
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. PELDOR Measurements on Nitroxide-Labeled Oligonucleotides.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  15. Chemical communications (Cambridge, England) · 2021
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Yin YangDepartment of Chemical and Biological Physics , Weizmann Institute of Science , Rehovot 76100 , Israel.
Bin-Bin PanState Key Laboratory of Elemento-organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering , Nankai University , Tianjin 300071 , China.
Xiaoli TanTianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy , Tianjin Medical University , Tianjin 300070 , China.
Feng YangState Key Laboratory of Elemento-organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering , Nankai University , Tianjin 300071 , China.
Yangping LiuTianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy , Tianjin Medical University , Tianjin 300070 , China.ORCID http://orcid.org/0000-0001-5455-3602
Xun-Cheng SuState Key Laboratory of Elemento-organic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering , Nankai University , Tianjin 300071 , China.ORCID http://orcid.org/0000-0003-3051-0047
Daniella GoldfarbDepartment of Chemical and Biological Physics , Weizmann Institute of Science , Rehovot 76100 , Israel.ORCID http://orcid.org/0000-0001-5714-7159
Nankai University · CNTianjin Medical University · CNWeizmann Institute of Science · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Double-electron electron resonance (DEER) can be used to track the structural dynamics of proteins in their native environment, the cell. This method provides the distance distribution between two spin labels attached at specific, well-defined positions in a protein. For the method to be viable under in-cell conditions, the spin label and its attachment to the protein should exhibit high chemical stability in the cell. Here we present low-temperature, trityl-trityl DEER distance measurements on two model proteins, PpiB (prolyl cis-trans isomerase from

Indexed as

Electron Spin Resonance SpectroscopyBacterial ProteinsCarrier ProteinsCyclophilinsGadoliniumSpin LabelsTriphenylmethyl CompoundsBacterial ProteinsCarrier Proteinscyclophilin BCyclophilinsGadoliniumimmunoglobulin G-binding protein, Streptococcus suis type 2Spin LabelsTriphenylmethyl Compounds

Identifiers

PMID31951412
PMCPMC7307952
OpenAlexW2999475378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.