ArticleeLife2020
Dynamic post-translational modification profiling of
Open access · goldAbstract read
In one paragraph
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
1.0field-weighted citation impact, top 13% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 69 citations in OpenAlex.
- Autophagy and selective autophagy receptors: Key players against Alzheimer's disease.Neural regeneration research · 2026Article
- Ubiquitylation by the GID/CTLH complex regulates the metabolic and innate immune response of macrophages to infection by Mycobacterium tuberculosis.PLoS pathogens · 2026Article
- HnRNPA2B1 tunes antimycobacterial immune responses in macrophages through alternative splicing ofInfection and immunity · 2026Article
- The ubiquitin ligase CBL and Fas-associated factor 2 cooperate to regulate the innate immune response to M. tuberculosis.PLoS pathogens · 2026Article
- Cysteine Reactivity Profiling Identifies Host Regulators ofACS infectious diseases · 2026Article
- HnRNPA2B1 tunes antimycobacterial immune responses in macrophages through alternative splicing ofbioRxiv : the preprint server for biology · 2025Article
- Mycobacterium tuberculosis triggers reduced inflammatory cytokine responses and virulence in mice lacking Tax1bp1.PLoS pathogens · 2025Article
- Cysteine reactivity profiling identifies host regulators ofbioRxiv : the preprint server for biology · 2025Article
- Plans within plans: post-transcriptional regulation governs macrophage responses.Trends in immunology · 2025Review
- Review
- HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma.Cancer research · 2025Article
- Article
- Insights into the protein ubiquitinome in the host‒pathogen interplay duringFrontiers in molecular biosciences · 2025Article
- Autophagy in mycobacterial infections: molecular mechanisms, host-pathogen interactions, and therapeutic opportunities.Frontiers in cellular and infection microbiology · 2025Review
- Tax1bp1 enhances bacterial virulence and promotes inflammatory responses duringbioRxiv : the preprint server for biology · 2024Article
- Integrative Multi-PTM Proteomics Reveals Dynamic Global, Redox, Phosphorylation, and Acetylation Regulation in Cytokine-Treated Pancreatic Beta Cells.Molecular & cellular proteomics : MCP · 2024Article
- Review
- The balance between antiviral and antibacterial responses duringbioRxiv : the preprint server for biology · 2024Article
- RNA Binding Proteins that Mediate LPS-induced Alternative Splicing of the MyD88 Innate Immune Regulator.Journal of molecular biology · 2024Article
- Serine/arginine-rich splicing factor 7 promotes the type I interferon response by activating Irf7 transcription.Cell reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 1 country.
Jonathan M BudzikDepartment of Medicine, University of California, San Francisco, San Francisco, United States.ORCID 0000-0001-8025-7911
Danielle L SwaneyDepartment of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.ORCID 0000-0001-6119-6084
David Jimenez-MoralesDepartment of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.
Jeffrey R JohnsonDepartment of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.
Nicholas E GarelisDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
Teresa RepasyDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
Allison W RobertsDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0001-6681-4144
Lauren M PopovDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
Trevor J ParryDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
Dexter PrattDepartment of Medicine, University of California, San Diego, La Jolla, United States.
Trey IdekerDepartment of Medicine, University of California, San Diego, La Jolla, United States.
Nevan J KroganDepartment of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, United States.
Jeffery S CoxDepartment of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0002-5061-6618
University of California, Berkeley · USGladstone Institutes · USUniversity of California San Diego · USUniversity of California, San Francisco · US
Funding
X-ray Screening and Rapid Structure DeterminationP50GM082250 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KROGAN, NEVAN J · 2007 to 2018
$48.8MThe role of Listeria cyclic-di-AMP during infection and immunityP01AI063302 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI PORTNOY, DANIEL A · 2004 to 2025
$45.5MVirus CoreU19AI106754 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DENNIS, EDWARD A · 2013 to 2017
$26.0MMUTIDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASEST32HL007185 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI David J Erle, LAURENCE HUANG · 1985 to 2026
$24.6MRESEARCH PROJECT 2U19AI135990 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Nevan J Krogan · 2018 to 2026
$21.4MX-ray Screening and Rapid Structure DeterminationP50AI150476 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KROGAN, NEVAN J · 2019 to 2021
$14.4MHost-Directed Strategies to Create Synergistic Antibacterial TherapiesDP1AI124619 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COX, JEFFERY S · 2015 to 2019
$3.9MEpigenetic & Post-Translational Mechanisms of Macrophage Resistance to Mycobacterium tuberculosis During HIV Co-InfectionR33AI138272 · NIAID · UNIVERSITY OF WASHINGTON · PI BOOM, W. HENRY, HAWN, THOMAS R · 2020 to 2022
$3.4MDiscovery of novel, ubiquitin-regulated mechanisms of TB control by macrophagesR01AI120694 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COX, JEFFERY S, KROGAN, NEVAN J · 2015 to 2019
$3.3MUCSF Career Development Program in Omics of Lung DiseasesK12HL119997 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURCHARD, ESTEBAN GONZALEZ, ERLE, DAVID J · 2013 to 2017
$1.4MAutomated High-Throughput, High-Content Confocal/Wide-Field Microscope SystemS10OD021828 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI WEST, MARY · 2017 to 2017
$1.0MDeciphering the role of autophagy receptor phosphorylation and host kinases in the targeting of M. tuberculosis to autophagyK08AI146267 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUDZIK, JONATHAN M · 2019 to 2023
$995kNational Institute of Allergy and Infectious Diseases 1K08AI146267NHLBI NIH HHS K12 HL119997NHLBI NIH HHS T32 HL007185NIAID NIH HHS DP1 AI124619NIAID NIH HHS K08 AI146267NIAID NIH HHS P01 AI063302NIAID NIH HHS P50 AI150476NIAID NIH HHS R01 AI120694NIAID NIH HHS R33 AI138272NIAID NIH HHS U19 AI106754NIAID NIH HHS U19 AI135990NIGMS NIH HHS P50 GM082250NIH HHS S10 OD021828
Abstract
Macrophages are highly plastic cells with critical roles in immunity, cancer, and tissue homeostasis, but how these distinct cellular fates are triggered by environmental cues is poorly understood. To uncover how primary murine macrophages respond to bacterial pathogens, we globally assessed changes in post-translational modifications of proteins during infection with
Indexed as
Protein Processing, Post-TranslationalAnimalsAutophagyBacterial ProteinsHumansMacrophagesMiceMycobacterium tuberculosisPhosphorylationProteomeTuberculosisUbiquitinationBacterial ProteinsProteomeautophagyinfectious diseasemacrophagemicrobiologypost-translational modificationproteomicstuberculosis
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.