Evidence map›Paper›PMID 31951115›Full record

ArticleChemical research in toxicology2020

Exposure to Trichloroethylene Metabolite

Elana R Elkin, Dave Bridges, Sean M Harris, Rita Karen Loch-Caruso

Open access · greenAbstract read
In one paragraph

Article in Chemical research in toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Trichloroethylene MetaboliteChemical research in toxicology · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Placenta as a target of trichloroethylene toxicity.Environmental science. Processes & impacts · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elana R ElkinDepartment of Environmental Health Sciences, University of Michigan, Ann Arbor, Michigan 48109-2029, United States.ORCID 0000-0001-8637-1731
Dave BridgesDepartment of Nutritional Sciences, University of Michigan, Ann Arbor, Michigan 48109-2029, United States.
Sean M HarrisDepartment of Environmental Health Sciences, University of Michigan, Ann Arbor, Michigan 48109-2029, United States.
Rita Karen Loch-CarusoDepartment of Environmental Health Sciences, University of Michigan, Ann Arbor, Michigan 48109-2029, United States.
University of Michigan · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Research Experiences and Training Coordination CoreP42ES017198 · NIEHS · NORTHEASTERN UNIVERSITY · PI HARRIS, SEAN M · 2010 to 2024
$38.6M
Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kanakadurga Singer · 2010 to 2026
$20.3M
ENVIRONMENTAL TOXICOLOGY PRE/POST DOCTORAL RES.TRAININGT32ES007062 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin Adam Colacino · 1985 to 2026
$10.5M
Regulation of Lipid Storage by mTORC1R01DK107535 · NIDDK · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI BRIDGES, DAVE · 2016 to 2020
$1.7M
NCATS NIH HHS UL1 TR002240NIDDK NIH HHS P30 DK089503NIDDK NIH HHS R01 DK107535NIEHS NIH HHS P30 ES017885NIEHS NIH HHS P42 ES017198NIEHS NIH HHS T32 ES007062
6 · The paper itself

Abstract

Trichloroethylene (TCE) is a widespread environmental contaminant following decades of use as an industrial solvent, improper disposal, and remediation challenges. Consequently, TCE exposure continues to constitute a risk to human health. Despite epidemiological evidence associating exposure with adverse birth outcomes, the effects of TCE and its metabolite

Indexed as

Amino AcidsAMP-Activated Protein KinasesCell LineCell SurvivalCysteineEnergy MetabolismGlucoseGlycerolHumansLipid MetabolismNutrientsPhosphofructokinase-1SolventsTrichloroethyleneAmino AcidsAMP-Activated Protein KinasesCysteineGlucoseGlycerolNutrientsPhosphofructokinase-1PRKAA1 protein, humanS-(1,2-dichlorovinyl)cysteineSolventsTrichloroethylene

Identifiers

PMID31951115
PMCPMC7299793
OpenAlexW3000269518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.