Evidence map›Paper›PMID 31950731›Full record

ReviewESC heart failure2020

Methamphetamine-related cardiovascular diseases.

Valentin Schwarzbach, Karsten Lenk, Ulrich Laufs

Registry-linked trialOpen access · goldAbstract readCase ReportsReview
In one paragraph

Review in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07459244 (Electrocardiogram Findings in Methamphetamine Use Disorder and Methamphetamine-Induced Psychotic Disorder), which is not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07459244 recruitingnot on this mapstarted 2025, after this paper: background citation

Electrocardiogram Findings in Methamphetamine Use Disorder and Methamphetamine-Induced Psychotic Disorder: A Prospective Observational Cohort Study

TypeobservationalSponsorElazığ Mental Health and Diseases HospitalRan2025 to 2026Enrolled240ConditionsMethamphetamine Use Disorder, Methamphetamine Induced Psychosis
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 50 citations in OpenAlex.

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  11. Respiratory Depression Associated with Opioids: A Narrative Review.Current treatment options in oncology · 2024
    Review
  12. Article
  13. Article
  14. Challenges and insights: Methamphetamine analysis in post-mortem putrefied human tissues in a hot climate.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Valentin SchwarzbachKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Leipzig, Germany.
Karsten LenkKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Leipzig, Germany.
Ulrich LaufsKlinik und Poliklinik für Kardiologie, Universitätsklinikum Leipzig, Leipzig, Germany.
Klinik und Poliklinik für Neurologie · DEUniversity Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsAbuse of crystal methamphetamine (MA) poses a growing problem for health services worldwide. This review summarizes the current literature on the effects of MA on the cardiovascular system. METHODS AND

resultsThis article is a presentation of a case report and review of the current literature. In Europe, especially the eastern countries and the eastern states of Germany are affected. MA increases the concentration of catecholamines in the synaptic gap leading to euphoria, alertness, and hunger suppression as well as psychiatric and gastrointestinal complications. MA consumption is associated with hypertension, acute and chronic myocardial toxicity, stroke, coronary artery disease, and sudden cardiac death. Although many aspects of the underlying pathophysiology remain unknown, catecholamine-mediated pathologies appear to play an important role. The duration of MA consumption is the most important determinant for the prognosis.

conclusionsAwareness is needed as cardiac complications are important causes of morbidity and mortality in patients with MA consumption. Drug abstinence is the mainstay of therapy, cardiac and other complications should be treated according to the respective guidelines. Incompliance to therapy and frequent relapses are the main challenges for successful treatment. Further research is required to improve the understanding of this rapidly increasing cardiomyopathy.

Indexed as

Cardiovascular DiseasesMethamphetamineEuropeGermanyHeartHumansMethamphetamineCardiomyopathyCrystalEuropeHeart failureMethamphetamine

Identifiers

PMID31950731
PMCPMC7160483
OpenAlexW3000017005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.