Evidence map›Paper›PMID 31950333›Full record

ArticleInternational ophthalmology2020

Predictive factors of outcome of selective retina therapy for diabetic macular edema.

Manabu Yamamoto, Yoko Miura, Kumiko Hirayama, Takeya Kohno, Daijiro Kabata, Dirk Theisen-Kunde, Ralf Brinkmann, Shigeru Honda

Abstract read
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In one paragraph

Article in International ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Current Treatments for Diabetic Macular Edema.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Selective retina therapy (SRT) for macular serous retinal detachment associated with tilted disc syndrome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Manabu YamamotoDepartment of Ophthalmology and Visual Sciences, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan. shidai.srtmaia@gmail.com.ORCID http://orcid.org/0000-0001-6666-8706
Yoko MiuraMedical Laser Center Lübeck GmBH, Lübeck, Germany.
Kumiko HirayamaDepartment of Ophthalmology and Visual Sciences, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Takeya KohnoDepartment of Ophthalmology and Visual Sciences, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Daijiro KabataDepartment of Medical Statistics, Osaka City University Graduate School of Medicine, Osaka, Japan.
Dirk Theisen-KundeMedical Laser Center Lübeck GmBH, Lübeck, Germany.
Ralf BrinkmannMedical Laser Center Lübeck GmBH, Lübeck, Germany.
Shigeru HondaDepartment of Ophthalmology and Visual Sciences, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
Osaka City University · JPMedizinisches Laserzentrum Lübeck (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the predictive factors of clinical outcome of selective retina therapy (SRT) for diabetic macular edema (DME).

methodsThis retrospective study included 22 eyes of 22 patients (15 males and 7 females), who were treated with SRT for DME at the Department of Ophthalmology of Osaka City University Hospital and observed at least 6 months after the treatment. The mean age was 64 years (range 40-81). Thirteen of the 22 eyes (59%) had a treatment history other than SRT before. SRT laser (527 nm, 1.7 µs, 100 Hz) was used for treatment. Changes in the best-corrected visual acuity (BCVA) (logMAR) and central macular thickness (CMT) in optical coherence tomography were examined at baseline, 3-month follow-up, and 6-month follow-up. Factors associated with the rate of change in CMT at 3 and 6 months after SRT were examined.

resultsThe mean BCVA (logMAR) was 0.26 ± 0.31, 0.22 ± 0.27 and 0.23 ± 0.29 at baseline, 3 months and 6 months, respectively (p = 0.15 at 3 months, 0.40 at 6 months; compared to baseline). The mean CMT was 502 ± 163, 493 ± 204, and 416 ± 185 μm at baseline, 3 months, and 6 months, respectively (p = 0.69 at 3 months, 0.01 at 6 months; compared to baseline). The multivariate analysis found a significant negative association with previous macular photocoagulation (p = 0.03) at 3 months and a positive association with a history of insulin use (p = 0.02) and previous panretinal photocoagulation (p = 0.03) at 6 months after SRT.

conclusionThe CMT was significantly decreased at 6 months after SRT in DME. The history of insulin use and panretinal photocoagulation may positively and the history of macular photocoagulation may negatively affect the outcome of SRT, which must be considered when determining the therapeutic indications for SRT.

Indexed as

Disease ManagementAdultAgedAged, 80 and overAngiogenesis InhibitorsDiabetic RetinopathyFemaleFluorescein AngiographyFollow-Up StudiesFundus OculiGlucocorticoidsHumansInjections, IntraocularLaser CoagulationMacular EdemaMaleAngiogenesis InhibitorsGlucocorticoidsTriamcinolone AcetonideDiabetic retinopathyLaser therapyMacular edemaRetinal pigment epithelium

Identifiers

PMID31950333
OpenAlexW3000637332

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.