ArticleAnnals of biomedical engineering2020
Adaptive Ankle Resistance from a Wearable Robotic Device to Improve Muscle Recruitment in Cerebral Palsy.
Article in Annals of biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Control strategies used in lower limb exoskeletons for gait rehabilitation after brain injury: a systematic review and analysis of clinical effectiveness.Journal of neuroengineering and rehabilitation · 2023Pooled it
- Effect of mediolateral leg perturbations on walking balance in people with chronic stroke: A randomized controlled trial.PloS one · 2024Trial
- Case Report: Gait training using a wearable ankle-exoskeleton in a pediatric patient with Guillain-Barré syndrome.Frontiers in pediatrics · 2026Article
- Predicting Steady-State Metabolic Power in Cerebral Palsy, Stroke, and the Elderly During Walking With and Without Assistive Devices.Annals of biomedical engineering · 2025Article
- Advancing Gait Rehabilitation: A Systematic Review of Robotic Exoskeletons for Cerebral Palsy.Wearable technologies · 2025Review
- Functional resistance training during walking: do biomechanical and neural effects differ based on targeted joints?IEEE transactions on medical robotics and bionics · 2024Article
- Does crouch alter the effects of neuromuscular impairments on gait? A simulation study.Journal of biomechanics · 2024Article
- Multi-session adaptation to audiovisual and sensorimotor biofeedback is heterogeneous among adolescents with cerebral palsy.PloS one · 2024Article
- Article
- Audiovisual biofeedback amplifies plantarflexor adaptation during walking among children with cerebral palsy.Journal of neuroengineering and rehabilitation · 2023Article
- Factors influencing neuromuscular responses to gait training with a robotic ankle exoskeleton in cerebral palsy.Assistive technology : the official journal of RESNA · 2023Article
- Predicting Neuromuscular Engagement to Improve Gait Training with a Robotic Ankle Exoskeleton.IEEE robotics and automation letters · 2023Article
- Ankle-targeted exosuit resistance increases paretic propulsion in people post-stroke.Journal of neuroengineering and rehabilitation · 2023Article
- Functional Resistance Training With Viscous and Elastic Devices: Does Resistance Type Acutely Affect Knee Function?IEEE transactions on bio-medical engineering · 2023Article
- A machine learning approach to quantify individual gait responses to ankle exoskeletons.bioRxiv : the preprint server for biology · 2023Article
- Mechanical disturbances applied by motorized ankle foot orthosis to adapt ankle muscles activation-A validation study.Frontiers in bioengineering and biotechnology · 2023Article
- Interleaved Assistance and Resistance for Exoskeleton Mediated Gait Training: Validation, Feasibility and Effects.Proceedings of the ... IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics. IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics · 2022Article
- Soleus H-reflex modulation in cerebral palsy and its relationship with neural control complexity: a pilot study.Experimental brain research · 2022Article
- Application of Wearable Sensors in Actuation and Control of Powered Ankle Exoskeletons: A Comprehensive Review.Sensors (Basel, Switzerland) · 2022Review
- Feasibility evaluation of a dual-mode ankle exoskeleton to assist and restore community ambulation in older adults.Wearable technologies · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Individuals with cerebral palsy can have weak and poorly coordinated ankle plantar flexor muscles that contribute to inefficient walking patterns. Previous studies attempting to improve plantar flexor function have had inconsistent effects on mobility, likely due to a lack of task-specificity. The goal of this study was to develop, validate, and test the feasibility and neuromuscular response of a novel wearable adaptive resistance platform to increase activity of the plantar flexors during the propulsive phase of gait. We recruited eight individuals with spastic cerebral palsy to walk with adaptive plantar flexor resistance provided from an untethered exoskeleton. The resistance system and protocol was safe and feasible for all of our participants. Controller validation demonstrated our ability to provide resistance that proportionally- and instantaneously-adapted to the biological ankle moment (R = 0.92 ± 0.04). Following acclimation to resistance (0.16 ± 0.02 Nm/kg), more-affected limbs exhibited a 45 ± 35% increase in plantar flexor activity (p = 0.02), a 26 ± 24% decrease in dorsiflexor activity (p < 0.05), and a 46 ± 25% decrease in co-contraction (tibialis anterior and soleus) (p = 0.02) during the stance phase. This adaptive resistance system warrants further investigation for use in a longitudinal intervention study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.