Evidence map›Paper›PMID 31950298›Full record

ArticleThe international journal of cardiovascular imaging2020

Cardiovascular magnetic resonance feature tracking in pigs: a reproducibility and sample size calculation study.

A Faragli, R Tanacli, C Kolp, T Lapinskas, C Stehning, B Schnackenburg, F P Lo Muzio, S Perna, B Pieske, E Nagel and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The international journal of cardiovascular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Cardiac Phase-Resolved TBiomedicines · 2025
    Article
  3. Article
  4. Article
  5. Pulmonary 4D-flow MRI imaging in landrace pigs under rest and stress.The international journal of cardiovascular imaging · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Cardiovascular magnetic resonance-derived left ventricular mechanics-strain, cardiac power and end-systolic elastance under various inotropic states in swine.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 4 countries.

A FaragliDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburgerplatz 1, 13353, Berlin, Germany.
R TanacliDepartment of Internal Medicine / Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
C KolpDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburgerplatz 1, 13353, Berlin, Germany.
T LapinskasDepartment of Internal Medicine / Cardiology, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
C StehningClinical Science, Philips Healthcare, Röntgenstr. 24, 22335, Hamburg, Germany.
B SchnackenburgClinical Science, Philips Healthcare, Röntgenstr. 24, 22335, Hamburg, Germany.
F P Lo MuzioDepartment of Surgery, Dentistry, Paedriatics and Gynaecology, University of Verona, Via S. Francesco 22, 37129, Verona, Italy.
S PernaDepartment of Biology, College of Science, University of Bahrain, Sakhir Campus, P.O. Box 32038, Zallaq, Bahrain.
B PieskeDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburgerplatz 1, 13353, Berlin, Germany.
E NagelInstitute of Experimental and Translational Cardiac Imaging, DZHK Centre for Cardiovascular Imaging, Goethe University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.
H PostDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburgerplatz 1, 13353, Berlin, Germany.
S KelleDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburgerplatz 1, 13353, Berlin, Germany.
A AlognaDepartment of Internal Medicine and Cardiology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum, Augustenburgerplatz 1, 13353, Berlin, Germany. alessio.alogna@charite.de.ORCID http://orcid.org/0000-0001-5988-2720
German Centre for Cardiovascular Research · DEDeutsches Herzzentrum der Charité · DEPhilips (Germany) · DECharité - Universitätsmedizin Berlin · DEGoethe University Frankfurt · DELithuanian University of Health Sciences · LTSt. Marien Hospital · DEUniversity of Bahrain · BHUniversity of Verona · IT

Funding

Deutsches Zentrum für Herz-Kreislaufforschung 81X2100305
6 · The paper itself

Abstract

Cardiovascular magnetic resonance feature tracking (CMR-FT) is a novel technique for non-invasive assessment of myocardial motion and deformation. Although CMR-FT is standardized in humans, literature on comparative analysis from animal models is scarce. In this study, we measured the reproducibility of global strain under various inotropic states and the sample size needed to test its relative changes in pigs. Ten anesthetized healthy Landrace pigs were investigated. After baseline (BL), two further steps were performed: (I) dobutamine-induced hyper-contractility (Dob) and (II) verapamil-induced hypocontractility (Ver). Global longitudinal (GLS), circumferential (GCS) and radial strain (GRS) were assessed. This study shows a good to excellent inter- and intra-observer reproducibility of CMR-FT in pigs under various inotropic states. The highest inter-observer reproducibility was observed for GLS at both BL (ICC 0.88) and Ver (ICC 0.79). According to the sample size calculation for GLS, a small number of animals could be used for future trials.

Indexed as

Magnetic Resonance Imaging, CineMyocardial ContractionVentricular Function, LeftAdrenergic beta-1 Receptor AgonistsAnesthesia, GeneralAnimalsCalcium Channel BlockersDobutamineFemaleHeart VentriclesModels, AnimalObserver VariationPredictive Value of TestsReproducibility of ResultsSample SizeSus scrofaAdrenergic beta-1 Receptor AgonistsCalcium Channel BlockersDobutamineVerapamilCardiovascular magnetic resonanceFeature trackingLeft ventricular strainPorcine modelReproducibilitySample size

Identifiers

PMID31950298
PMCPMC7125242
OpenAlexW2998917692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.