Evidence map›Paper›PMID 31950189›Full record

ArticleDatabase : the journal of biological databases and curation2020

RNA CoSSMos 2.0: an improved searchable database of secondary structure motifs in RNA three-dimensional structures.

Katherine E Richardson, Charles C Kirkpatrick, Brent M Znosko

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Katherine E RichardsonSaint Louis University, Department of Chemistry, 3501 Laclede Avenue, St. Louis, MO 63103 USA.
Charles C KirkpatrickSaint Louis University, Department of Chemistry, 3501 Laclede Avenue, St. Louis, MO 63103 USA.
Brent M ZnoskoSaint Louis University, Department of Chemistry, 3501 Laclede Avenue, St. Louis, MO 63103 USA.

Funding

Understanding the Thermodynamics and Structure of RNA Secondary Structure MotifsR15GM085699 · NIGMS · SAINT LOUIS UNIVERSITY · PI ZNOSKO, BRENT · 2009 to 2025
$2.0M
NIGMS NIH HHS R15 GM085699
6 · The paper itself

Abstract

The RNA Characterization of Secondary Structure Motifs, RNA CoSSMos, database is a freely accessible online database that allows users to identify secondary structure motifs among RNA 3D structures and explore their structural features. RNA CoSSMos 2.0 now requires two closing base pairs for all RNA loop motifs to create a less redundant database of secondary structures. Furthermore, RNA CoSSMos 2.0 represents an upgraded database with new features that summarize search findings and aid in the search for 3D structural patterns among RNA secondary structure motifs. Previously, users were limited to viewing search results individually, with no built-in tools to compare search results. RNA CoSSMos 2.0 provides two new features, allowing users to summarize, analyze and compare their search result findings. A function has been added to the website that calculates the average and representative structures of the search results. Additionally, users can now view a summary page of their search results that reports percentages of each structural feature found, including sugar pucker, glycosidic linkage, hydrogen bonding patterns and stacking interactions. Other upgrades include a newly embedded NGL structural viewer, the option to download the clipped structure coordinates in *.pdb format and improved NMR structure results. RNA CoSSMos 2.0 is no longer simply a search engine for a structure database; it now has the capability of analyzing, comparing and summarizing search results. Database URL: http://rnacossmos.com.

Indexed as

Databases, Nucleic AcidNucleic Acid ConformationNucleotide MotifsRNAUser-Computer InterfaceRNA

Identifiers

PMID31950189
PMCPMC6966092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.