ArticleJournal of experimental botany2020
The mirid bug Apolygus lucorum deploys a glutathione peroxidase as a candidate effector to enhance plant susceptibility.
Article in Journal of experimental botany, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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26 citing papers in PubMed, 65 citations in OpenAlex.
- An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs HAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Resilience of floral scent emission after florivory.Plant biology (Stuttgart, Germany) · 2026Article
- Three Decades of China's Bt Cotton: Achievements and Insights.Plant biotechnology journal · 2026Review
- Identification of Oral Secretion Proteins inInsects · 2026Article
- A pentatomomorpha-specific salivary protein activates plant immunity and is critical for insect feeding.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Proteomic Variation in the Oral Secretion of Spodoptera exigua and Spodoptera littoralis Larvae in Response to Different food Sources.Journal of chemical ecology · 2025Article
- Bacteria Derived from Diamondback Moth,Insects · 2024Article
- Cotton Bollworm (H. armigera) Effector PPI5 Targets FKBP17-2 to Inhibit ER Immunity and JA/SA Responses, Enhancing Insect Feeding.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- The molecular dynamics between reactive oxygen species (ROS), reactive nitrogen species (RNS) and phytohormones in plant's response to biotic stress.Plant cell reports · 2024Review
- An effector ofiScience · 2024Article
- Transcriptomic analysis of the defense response in "Cabernet Sauvignon" grape leaf induced byPlant direct · 2024Article
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- Roles of herbivorous insects salivary proteins.Heliyon · 2024Review
- A pipeline contributes to efficient identification of salivary proteins in short-headed planthopper, Epeurysa nawaii.Scientific reports · 2024Article
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- Protein Profiling ofInternational journal of molecular sciences · 2023Article
- A salivary secretory protein from Riptortus pedestris facilitates pest infestation and soybean staygreen syndrome.Molecular plant pathology · 2023Article
- Bringing Fundamental Insights of Induced Resistance to Agricultural Management of Herbivore Pests.Journal of chemical ecology · 2023Review
- Planthopper salivary sheath protein LsSP1 contributes to manipulation of rice plant defenses.Nature communications · 2023Article
- TheHorticulture research · 2023Article
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mirid bug Apolygus lucorum has become a major agricultural pest since the large-scale cultivation of Bt-cotton. It was assumed that A. lucorum, similarly to other phloem sap insects, could secrete saliva that contains effector proteins into plant interfaces to perturb host cellular processes during feeding. However, the secreted effectors of A. lucorum are still uncharacterized and unstudied. In this study, 1878 putative secreted proteins were identified from the transcriptome of A. lucorum, which either had homology with published aphid effectors or shared common features with plant pathogens and insect effectors. One hundred and seventy-two candidate effectors were used for cell death-inducing/suppressing assays, and a putative salivary gland effector, Apolygus lucorum cell death inhibitor 6 (Al6), was characterized. The mRNAs of Al6 were enriched at feeding stages (nymph and adult) and, in particular, in salivary glands. Moreover, we revealed that the secreted Al6 encoded an active glutathione peroxidase that reduced reactive oxygen species (ROS) accumulation induced by INF1 or Flg22. Expression of the Al6 gene in planta altered insect feeding behavior and promoted plant pathogen infections. Inhibition of cell death and enhanced plant susceptibility to insect and pathogens are dependent on glutathione peroxidase activity of Al6. Thus, this study shows that a candidate salivary gland effector, Al6, functions as a glutathione peroxidase and suppresses ROS induced by pathogen-associated molecular pattern to inhibit pattern-triggered immunity (PTI)-induced cell death. The identification and molecular mechanism analysis of the Al6 candidate effector in A. lucorum will provide new insight into the molecular mechanisms of insect-plant interactions.
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