Evidence map›Paper›PMID 31950055›Full record

ArticleBioMed research international2019

All-Trans Retinoic Acid Enhances Bacterial Flagellin-Stimulated Proinflammatory Responses in Human Monocyte THP-1 Cells by Upregulating CD14.

Thi Xoan Hoang, Jong Hyeok Jung, Jae Young Kim

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Comparative analysis of ipsilateral versus contralateral inclinatory approaches in unilateral biportal endoscopic lumbar discectomy and strategies to reduce recurrence.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  6. Understanding immune-modulatory efficacy in vitro.Chemico-biological interactions · 2022
    Review
  7. The role of the retinoid receptor, RAR/RXR heterodimer, in liver physiology.Biochimica et biophysica acta. Molecular basis of disease · 2021
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Thi Xoan HoangDepartment of Life Science, Gachon University, Seongnam, Gyeonggi-Do 461-701, Republic of Korea.ORCID https://orcid.org/0000-0003-0401-5843
Jong Hyeok JungDepartment of Life Science, Gachon University, Seongnam, Gyeonggi-Do 461-701, Republic of Korea.
Jae Young KimDepartment of Life Science, Gachon University, Seongnam, Gyeonggi-Do 461-701, Republic of Korea.ORCID https://orcid.org/0000-0001-9323-3580
Gachon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All-trans retinoic acid (ATRA), an active form of vitamin A, exerts immunomodulatory functions. In this study, we examined the immune potentiating effect of ATRA on bacterial flagellin-induced NF-

Indexed as

FlagellinGene Expression RegulationHumansInflammationInterleukin-1betaLipopolysaccharide ReceptorsMonocytesNF-kappa BReceptors, Retinoic AcidRetinoid X ReceptorsSignal TransductionTHP-1 CellsToll-Like Receptor 5TretinoinTumor Necrosis Factor-alphaFlagellinInterleukin-1betaLipopolysaccharide ReceptorsNF-kappa BReceptors, Retinoic AcidRetinoid X ReceptorsTLR5 protein, humanToll-Like Receptor 5TretinoinTumor Necrosis Factor-alpha

Identifiers

PMID31950055
PMCPMC6948301
OpenAlexW2996927716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.