ArticleInternational journal of clinical and experimental pathology2018
Testicular germ cell tumors: a clinicopathological and immunohistochemical analysis of 145 cases.
Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 11 citations in OpenAlex.
- KDM4A drives TGCT metastasis by inducing focal adhesion disassembly via STAT1-mediated CCL3 transcriptional activation.Oncogene · 2026Article
- SMARCB1-deficient poorly differentiated testicular carcinoma: a case report.Frontiers in oncology · 2025Article
- Diagnostic Value of SALL4 and OCT3/4 in Pediatric Testicular Tumors.Diagnostics (Basel, Switzerland) · 2024Article
- Lymph Node Dissection in Testicular Cancer: The State of the Art and Future Perspectives.Current oncology reports · 2024Review
- Article
- Testicular yolk sac tumour metastasis to the L2 vertebra.BMJ case reports · 2022Article
- RNA-Binding Proteins Play an Important Role in the Prognosis of Patients With Testicular Germ Cell Tumor.Frontiers in genetics · 2021Article
- The core four - A panel of immunohistochemistry markers to diagnose and subtype testicular germ cell tumors.Urology annalsArticle
- Characterization of DDX4 Gene Expression in Human Cases with Non-Obstructive Azoospermia and in Sterile and Fertile Mice.Journal of reproduction & infertilityArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Testicular germ cell tumor (TGCT) is the most common tumor usually occuring in males between 20-40 years old. In recentyears, the incidence of TGCTs has risen markedly. The outcome depends on its pathologic type and tumor stage. This study was a retrospective analysis of the clinicopathological and immunohistochemical of 145 TGCTs. According to our findings, teratoma, both mature and immature, mostly involved children, as did yolk sac tumor. Patients under 18 years old all survived for at least five years, while the mortality rate was 87.8% after five years since surgery and 96.5% in adults after three years. There was no difference between the survival rate of seminomatous tumor and non-seminomatous tumor. We also analyzed two routine diagnostic markers-PLAP and OCT4 on all TGCT tissues. Results showed that OCT4 may be a better predictive marker than PLAP to distinguish the TGCTS. Our finding suggested that TGCTs mostly occurred in young adult, and the mortality of those who under 18 years old is lower than the adult patients. However in distinguishing the seminoma tumor from non-seminoma tumor, new marker should be further study.
Indexed as
Identifiers
31949861PMC6962990W3007441854What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.