ArticleInternational journal of clinical and experimental pathology2018
Down-regulation of LINC00341 predicts a poor prognosis and acts as a tumor suppressor in gastric cancer.
Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- LINC00341 promotes fracture healing through downregulation of miR-133a-3p.Journal of orthopaedic surgery and research · 2025Article
- The Role of Epigenetic Mechanisms in the Treatment of GI Cancers.Current cancer drug targets · 2025Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
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Abstract
Accumulating evidence has suggested that long noncoding RNAs (lncRNAs) play critical roles in tumor cell development and in the progression of human cancer. However, the significance and role of most lncRNAs, especially long intergenic ncRNAs (lincRNAs, the main type of lncRNAs), in gastric cancer is unclear. This study aimed to identify the clinical significance and potential biological function of LINC00341 in gastric cancer. Here, a qRT-PCR assay indicated that the relative expression level of LINC00341 were significantly down-regulated in gastric cancer tissues compared to matched adjacent normal tissues. Levels of LINC00341 in gastric cancer cell lines (MGC-803, BGC-823 and SGC-7901) were also significantly lower than in human normal gastric epithelial cell (GES-1). Patient with low LINC00341 expression were found to be negatively correlated with the TNM stage and lymph node metastasis. A Kaplan-Meier analysis showed that low expression of LINC00341 was significantly correlated with shorter overall survival (OS) of gastric cancer patients. Furthermore, an
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Identifiers
31949815PMC6962788W3028395391What OpenQuestion holds
Registered trials
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