Evidence map›Paper›PMID 31949752›Full record

ArticleInternational journal of clinical and experimental pathology2018

High CHD9 expression is associated with poor prognosis in clear cell renal cell carcinoma.

Bo Guan, Xian-Gui Ran, Yong-Qiang Du, Feng Ren, Ye Tian, Ying Wang, Ming-Min Chen

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Bo GuanDepartment of Urology, Capital Medical University, Beijing Friendship Hospital Beijing, P. R. China.
Xian-Gui RanDepartment of Respiratory and Critical Care Medicine, Fuyang People's Hospital Yingzhou District, Fuyang, Anhui Province, P. R. China.
Yong-Qiang DuDepartment of Urology, Fuyang People's Hospital Yingzhou District, Fuyang, Anhui Province, P. R. China.
Feng RenYouan Hospital, Capital Medical University Beijing, P. R. China.
Ye TianDepartment of Urology, Capital Medical University, Beijing Friendship Hospital Beijing, P. R. China.
Ying WangShanghai Outdo Biotech Co., Ltd. Shanghai, P. R. China.
Ming-Min ChenShanghai Outdo Biotech Co., Ltd. Shanghai, P. R. China.
Fuyang City People's Hospital · CNViva Biotech (China) · CNBeijing Friendship Hospital · CNBeijing YouAn Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma. The chromo-helicase-DNA binding proteins (CHDs), containing nine members named CHD1-9, act as regulators of the chromatin remodeling process and gene expression. To determine the correlation between CHD9 expression and ccRCC, we performed an immunohistochemical staining in a tissue microarray (TMAs) containing tissue samples from 88 ccRCC patients. The results showed that cytoplasm CHD9 expression was statistically decreased in tumor tissues compared to adjacent tissues (8.54±2.90 vs 12.61±2.05,

Indexed as

CHD9chemotherapyclear cell renal cell carcinoma (ccRCC)immunohistochemistrysurvival timetissue microarray

Identifiers

PMID31949752
PMCPMC6962849
OpenAlexW3028494198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.