Evidence map›Paper›PMID 31949718›Full record

ArticleInternational journal of clinical and experimental pathology2018

MiR-206 is down-regulated and suppresses cell proliferation by targeting FOXP1 in brain gliomas.

Lei Du, Guo-Hao Huang, Ke-Jie Mou, Yan Xiang, Jun-Hai Tang, Wu Xu, Shu-Li Xia, Jian-Nong Zhao, Sheng-Qing Lv

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Lei DuDepartment of Neurosurgery, Xinqiao Hospital, Third Military Medical University Chongqing 400037, China.
Guo-Hao HuangDepartment of Neurosurgery, Xinqiao Hospital, Third Military Medical University Chongqing 400037, China.
Ke-Jie MouDepartment of Neurosurgery, Bishan Hospital, Chongqing Medical University Chongqing 402760, China.
Yan XiangDepartment of Neurosurgery, Xinqiao Hospital, Third Military Medical University Chongqing 400037, China.
Jun-Hai TangDepartment of Neurosurgery, Xinqiao Hospital, Third Military Medical University Chongqing 400037, China.
Wu XuDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University Changsha 410078, China.
Shu-Li XiaDepartment of Neurology, Hugo W. Moser Research Institute at Kennedy Krieger, Johns Hopkins School of Medicine Baltimore, MD 21205, USA.
Jian-Nong ZhaoDepartment of Neurosurgery, Hainan General Hospital Haikou 570311, China.
Sheng-Qing LvDepartment of Neurosurgery, Xinqiao Hospital, Third Military Medical University Chongqing 400037, China.
Army Medical University · CNCentral South University · CNHainan General Hospital · CNKennedy Krieger Institute · USPeople's Hospital of Bishan District · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aberrant expression of miR-206 has been repeatedly found and demonstrated to play crucial roles in cancers. However, the role of miR-206 in brain glioma remains unclear. To address this issue, we detected miR-206 expression of 60 gliomas and 18 normal peritumor tissues, and found that miR-206 is significantly down-regulated in gliomas. Further

Indexed as

brain gliomacell proliferationFOXP1miR-206

Identifiers

PMID31949718
PMCPMC6962847
OpenAlexW3027481866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.