Evidence map›Paper›PMID 31949715›Full record

ArticleInternational journal of clinical and experimental pathology2018

miR-26b inhibits total neurite outgrowth, promotes cells apoptosis and downregulates neprilysin in Alzheimer's disease.

Tingting Chu, Yongwei Shu, Yang Qu, Shasha Gao, Liming Zhang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Review
  3. Opioid-Induced Regulation of Cortical Circular-International journal of molecular sciences · 2025
    Article
  4. Article
  5. Review
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  12. Review
  13. Role of MicroRNAs in Parkinson's Disease.International journal of molecular sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Tingting ChuDepartment of Neurology, The First Affiliated Hospital of Harbin Medical University Harbin, China.
Yongwei ShuThe First Department of Neurology, The Fourth Affiliated Hospital of Harbin Medical University Harbin, China.
Yang QuThe First Department of Neurology, The Fourth Affiliated Hospital of Harbin Medical University Harbin, China.
Shasha GaoMedical Department, Peide Hospital Mishan, China.
Liming ZhangDepartment of Neurology, The First Affiliated Hospital of Harbin Medical University Harbin, China.
Harbin Medical University · CNTaishan Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the effect of miR-26b expression on neurites outgrowth and cells apoptosis in PC12 cellular model of Alzheimer's disease (AD). PC12 cells were stimulated by nerve growth factor and insulted by Aβ

Indexed as

Alzheimer’s diseaseapoptosismiR-26bneurite outgrowthPC12

Identifiers

PMID31949715
PMCPMC6962878
OpenAlexW3012171566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.