Evidence map›Paper›PMID 31949707›Full record

ArticleInternational journal of clinical and experimental pathology2018

IL-17 enhances oxidative stress in hepatocytes through Nrf2/keap1 signal pathway activation.

Xiaoheng Xu, Sijin Zhang, Xingyu Song, Qibo Hu, Wei Pan

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Innate immunity and early liver inflammation.Frontiers in immunology · 2023
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiaoheng XuDepartment of Pediatrics, The Second Hospital of Jilin University Changchun, Jilin, P. R. China.
Sijin ZhangDepartment of Pediatrics, The Second Hospital of Jilin University Changchun, Jilin, P. R. China.
Xingyu SongDepartment of Pediatrics, The Second Hospital of Jilin University Changchun, Jilin, P. R. China.
Qibo HuDepartment of Pediatrics, The Second Hospital of Jilin University Changchun, Jilin, P. R. China.
Wei PanDepartment of Pediatrics, The Second Hospital of Jilin University Changchun, Jilin, P. R. China.
Second Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic disease is common worldwide. As apoptosis of hepatocytes is a hallmark of hepatic disease, strategies targeting apoptosis are an effective way to prevent and treat the disease. Oxidative stress is a classic pathway of apoptosis. Increased expression of IL-17 has been found in diverse human liver diseases. The aim of this research was to investigate whether the function of IL-17 influenced hepatocyte-induced H

Indexed as

Hepatic diseasehepatocytesIL-17Nrf2/keap1 pathway

Identifiers

PMID31949707
PMCPMC6962824
OpenAlexW3027277832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.