Evidence map›Paper›PMID 31949555›Full record

ArticleInternational journal of clinical and experimental pathology2018

The clinicopathological characterization of small hepatocellular carcinoma with fibrous stroma.

Toshihiro Yagi, Yasuni Nakanuma, Yasunori Sato, Takeo Nitta, Motoko Sasaki, Toshifumi Gabata, Kenichi Harada

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Toshihiro YagiDepartment of Human Pathology, Kanazawa University Graduate School of Medicine Kanazawa, Japan.
Yasuni NakanumaDepartment of Diagnostic Pathology, Fukui-ken Saiseikai Hospital Fukui, Japan.
Yasunori SatoDepartment of Human Pathology, Kanazawa University Graduate School of Medicine Kanazawa, Japan.
Takeo NittaDepartment of Human Pathology, Kanazawa University Graduate School of Medicine Kanazawa, Japan.
Motoko SasakiDepartment of Human Pathology, Kanazawa University Graduate School of Medicine Kanazawa, Japan.
Toshifumi GabataDepartment of Radiology, Kanazawa University Graduate School of Medicine Kanazawa, Japan.
Kenichi HaradaDepartment of Human Pathology, Kanazawa University Graduate School of Medicine Kanazawa, Japan.
Kanazawa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies emphasized the significance of fibrous stroma affecting tumor biology in hepatocellular carcinoma (HCC). To further clarify fibrous stroma's significance, this study investigated the clinicopathological characteristics of HCC with fibrous stroma. A total of 214 nodules of HCC smaller than 3 cm in diameter were analyzed, and 22 (10%) were regarded as HCC with fibrous stroma. Most cases of HCC with fibrous stroma were the simple nodular type without a fibrous capsule, and histologically well- or moderately-differentiated. A subset of the scirrhous variant of HCC was included in this category, and steatohepatitic features, such as Mallory-Denk body formation and lymphoid infiltrates, were also frequently found. Foci with a histological appearance corresponding to dysplastic nodules and/or early HCC were rarely observed in HCC with fibrous stroma, suggesting that some cases occurred via a

Indexed as

fibrous stromahepatocarcinogenesisHepatocellular carcinomascirrhous HCCsteatohepatitic HCC

Identifiers

PMID31949555
PMCPMC6962937
OpenAlexW3004493121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.