Evidence map›Paper›PMID 31949423›Full record

ArticleMediators of inflammation2019

Role of SOCS2 in the Regulation of Immune Response and Development of the Experimental Autoimmune Encephalomyelitis.

Allysson Cramer, Bruno Cabral de Lima Oliveira, Paulo Gaio Leite, David Henrique Rodrigues, Fatima Brant, Lisia Esper, Pollyana Maria Oliveira Pimentel, Rafael Machado Rezende, Milene Alvarenga Rachid, Antonio Lucio Teixeira and 3 more

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  10. Review
  11. SOCS2 regulates alveolar bone loss in Aggregatibacter actinomycetemcomitans-induced periodontal disease.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 2 countries.

Allysson CramerDepartment of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0002-5682-3773
Bruno Cabral de Lima OliveiraDepartment of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0002-5243-7111
Paulo Gaio LeiteDepartment of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0003-3753-9547
David Henrique RodriguesDepartment of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0002-7072-3269
Fatima BrantDepartment of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0003-4520-689X
Lisia EsperDepartment of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0002-2644-8175
Pollyana Maria Oliveira PimentelDepartment of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0002-3050-1063
Rafael Machado RezendeDepartment of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0003-3998-8012
Milene Alvarenga RachidDepartment of Pathology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0002-3142-6552
Antonio Lucio TeixeiraProgram in Health Sciences, Infectious Diseases and Tropical Medicine/Interdisciplinary Laboratory of Medical Investigation, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Ana Maria Caetano FariaDepartment of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Mauro Martins TeixeiraDepartment of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0002-6944-3008
Fabiana Simão MachadoDepartment of Biochemistry and Immunology, Institute of Biological Science, Federal University of Minas Gerais, Belo Horizonte, Brazil.ORCID https://orcid.org/0000-0001-9272-5209
Universidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS). Experimental Autoimmune Encephalomyelitis (EAE) is the most widely used animal model for the study of MS. The Suppressor of Cytokine Signaling (SOCS) 2 protein plays a critical role in regulating the immune responses. The role of SOCS2 during EAE has not been explored. EAE was induced in WT and SOCS2

Indexed as

AnimalsBlotting, WesternCentral Nervous SystemEncephalomyelitis, Autoimmune, ExperimentalFemaleFlow CytometryInflammationMiceMice, Inbred C57BLMice, KnockoutSuppressor of Cytokine Signaling ProteinsTh17 CellsTh1 CellsTh2 CellsSocs2 protein, mouseSuppressor of Cytokine Signaling Proteins

Identifiers

PMID31949423
PMCPMC6942913
OpenAlexW2994740716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.