Evidence map›Paper›PMID 31949192›Full record

ArticleScientific reports2020

Incidence of breast cancer attributable to breast density, modifiable and non-modifiable breast cancer risk factors in Singapore.

Peh Joo Ho, Hannah Si Hui Lau, Weang Kee Ho, Fuh Yong Wong, Qian Yang, Ken Wei Tan, Min-Han Tan, Wen Yee Chay, Kee Seng Chia, Mikael Hartman and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Systematic Review and Meta-Analysis of Lifestyle and Reproductive Factors Associated with Risk of Breast Cancer in Asian Women.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
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  5. Integrating Knowledge of Modifiable and Non-modifiable Risk Factors: A Comprehensive Framework for Breast Cancer Prevention Practices in Women.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
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  7. Cancer Burden Across The South East Asia Nation (ASEAN) in 2022.Asian Pacific journal of cancer prevention : APJCP · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peh Joo HoGenome Institute of Singapore, 60 Biopolis Street, Genome, #02-01, Singapore, 138672, Singapore.
Hannah Si Hui LauGenome Institute of Singapore, 60 Biopolis Street, Genome, #02-01, Singapore, 138672, Singapore.
Weang Kee HoDepartment of Applied Mathematics, Faculty of Engineering, University of Nottingham Malaysia, Selangor, Malaysia.
Fuh Yong WongNational Cancer Centre Singapore, Singapore, Singapore.
Qian YangSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Ken Wei TanSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Min-Han TanNational Cancer Centre Singapore, Singapore, Singapore.
Wen Yee ChayNational Cancer Centre Singapore, Singapore, Singapore.
Kee Seng ChiaSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Mikael HartmanSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Jingmei LiGenome Institute of Singapore, 60 Biopolis Street, Genome, #02-01, Singapore, 138672, Singapore. lijm1@gis.a-star.edu.sg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Incidence of breast cancer is rising rapidly in Asia. Some breast cancer risk factors are modifiable. We examined the impact of known breast cancer risk factors, including body mass index (BMI), reproductive and hormonal risk factors, and breast density on the incidence of breast cancer, in Singapore. The study population was a population-based prospective trial of screening mammography - Singapore Breast Cancer Screening Project. Population attributable risk and absolute risks of breast cancer due to various risk factors were calculated. Among 28,130 women, 474 women (1.7%) developed breast cancer. The population attributable risk was highest for ethnicity (49.4%) and lowest for family history of breast cancer (3.8%). The proportion of breast cancers that is attributable to modifiable risk factor BMI was 16.2%. The proportion of breast cancers that is attributable to reproductive risk factors were low; 9.2% for age at menarche and 4.2% for number of live births. Up to 45.9% of all breast cancers could be avoided if all women had breast density <12% and BMI <25 kg/m

Indexed as

Body Mass IndexBreast DensityBreast NeoplasmsEarly Detection of CancerFemaleHumansIncidenceMammographyMiddle AgedProspective StudiesRisk AssessmentSingapore

Identifiers

PMID31949192
PMCPMC6965174

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.