Evidence map›Paper›PMID 31949189›Full record

ArticleScientific reports2020

Sleep/Wake Regularity Associated with Default Mode Network Structure among Healthy Adolescents and Young Adults.

Jessica R Lunsford-Avery, Katherine S F Damme, Matthew M Engelhard, Scott H Kollins, Vijay A Mittal

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jessica R Lunsford-AveryDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA. jessica.r.avery@duke.edu.
Katherine S F DammeDepartment of Psychology, Northwestern University, Evanston, IL, USA.
Matthew M EngelhardDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Scott H KollinsDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA.
Vijay A MittalDepartment of Psychology, Northwestern University, Evanston, IL, USA.
Duke University · USNorthwestern University · US

Funding

Frontal-Subcortical Development, Movement Abnormalities, and Risk for PsychosisR01MH094650 · NIMH · UNIVERSITY OF COLORADO · PI MITTAL, VIJAY A · 2011 to 2015
$2.3M
2/3 Community psychosis risk screening: An instrument development studyR01MH112545 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2017 to 2021
$1.2M
Sleep Dysfunction and Neurocognitive Outcomes in Adolescent ADHDK23MH108704 · NIMH · DUKE UNIVERSITY · PI LUNSFORD-AVERY, JESSICA RUTH · 2016 to 2022
$837k
Exercise and markers of medial temporal health in youth at-risk for psychosisR33MH103231 · NIMH · NORTHWESTERN UNIVERSITY · PI BRYAN, ANGELA, MITTAL, VIJAY A · 2016 to 2018
$689k
Exercise and markers of medial temporal health in youth at-risk for psychosisR21MH103231 · NIMH · UNIVERSITY OF COLORADO · PI BRYAN, ANGELA, MITTAL, VIJAY A · 2014 to 2015
$489k
6 · The paper itself

Abstract

Sleep deprivation and disorders are linked to reduced DMN connectivity. Less is known about how naturalistic sleep patterns - specifically sleep irregularity - relate to the DMN, particularly among adolescents and young adults. Additionally, no studies have utilized graph theory analysis to clarify whether sleep-related decreases in connectivity reflect global or local DMN changes. Twenty-five healthy adolescents and young adults (age range = 12-22; mean = 18.08; SD = 2.64, 56% female) completed 7 days of actigraphy and resting-state fMRI. Sleep regularity was captured by the Sleep Regularity Index (SRI) and the relationship between the SRI and DMN was examined using graph theory analysis. Analogous analyses explored relationships between the SRI and additional resting-state networks. Greater sleep regularity related to decreased path length (increased network connectivity) in DMN regions, particularly the right and left lateral parietal lobule, and the Language Network, including the left inferior frontal gyrus and the left posterior superior frontal gyrus. Findings were robust to covariates including sex and age. Sleep and DMN function may be tightly linked during adolescence and young adulthood, and reduced DMN connectivity may reflect local changes within the network. Future studies should assess how this relationship impacts cognitive development and neuropsychiatric outcomes in this age group.

Indexed as

ActigraphyAdolescentFemaleHealthy VolunteersHumansMagnetic Resonance ImagingMaleNeural PathwaysParietal LobePrefrontal CortexRestSleepYoung Adult

Identifiers

PMID31949189
PMCPMC6965093
OpenAlexW3000409025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.