ArticleNature communications2020
Neural circuits underlying auditory contrast gain control and their perceptual implications.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 69 citations in OpenAlex.
- Neuronal dynamics, timing, and flow of sensory and choice-related information in auditory-prefrontal circuitry.Nature communications · 2026Article
- Rethinking hierarchy: the auditory system as an integrated cortical-subcortical network.Nature reviews. Neuroscience · 2026Review
- Parvalbumin neurons and cortical coding of dynamic stimuli: a network model.Journal of neurophysiology · 2025Article
- Starch-Glycerol-Based Hydrogel Memristors for Bio-Inspired Auditory Neuron Applications.Gels (Basel, Switzerland) · 2025Article
- Article
- Subcortical origin of nonlinear sound encoding in auditory cortex.Current biology : CB · 2024Article
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- Article
- Cortical Zinc Signaling Is Necessary for Changes in Mouse Pupil Diameter That Are Evoked by Background Sounds with Different Contrasts.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Parvalbumin and Somatostatin: Biomarkers for Two Parallel Tectothalamic Pathways in the Auditory Midbrain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Dissociable Roles of the Auditory Midbrain and Cortex in Processing the Statistical Features of Natural Sound Textures.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Adaptive mechanisms facilitate robust performance in noise and in reverberation in an auditory categorization model.Communications biology · 2023Article
- Adaptation in auditory processing.Physiological reviews · 2023Review
- Selective corticofugal modulation on sound processing in auditory thalamus of awake marmosets.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Deep neural networks effectively model neural adaptation to changing background noise and suggest nonlinear noise filtering methods in auditory cortex.NeuroImage · 2023Article
- Neural substrates of perception in the vestibular thalamus during natural self-motion: A review.Current research in neurobiology · 2023Review
- Relative changes in the cochlear summating potentials to paired-clicks predict speech-in-noise perception and subjective hearing acuity.JASA express letters · 2022Article
- Neuromodulatory Mechanisms Underlying Contrast Gain Control in Mouse Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Cortical adaptation to sound reverberation.eLife · 2022Article
- Sensory adaptation mediates efficient and unambiguous encoding of natural stimuli by vestibular thalamocortical pathways.Nature communications · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Neural adaptation enables sensory information to be represented optimally in the brain despite large fluctuations over time in the statistics of the environment. Auditory contrast gain control represents an important example, which is thought to arise primarily from cortical processing. Here we show that neurons in the auditory thalamus and midbrain of mice show robust contrast gain control, and that this is implemented independently of cortical activity. Although neurons at each level exhibit contrast gain control to similar degrees, adaptation time constants become longer at later stages of the processing hierarchy, resulting in progressively more stable representations. We also show that auditory discrimination thresholds in human listeners compensate for changes in contrast, and that the strength of this perceptual adaptation can be predicted from physiological measurements. Contrast adaptation is therefore a robust property of both the subcortical and cortical auditory system and accounts for the short-term adaptability of perceptual judgments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.