Evidence map›Paper›PMID 31949037›Full record

ArticleLearning & memory (Cold Spring Harbor, N.Y.)2020

Depotentiation depends on IP

Satoshi Fujii, Yoshihiko Yamazaki, Jun-Ichi Goto, Hiroki Fujiwara, Katsuhiko Mikoshiba

Erratum issuedOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Learning & memory (Cold Spring Harbor, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Bioelectric; Neuromodulation; Epilepsy; DBS; High-frequency stimulation; Low frequency stimulation.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  2. Amyloid-β Causes NMDA Receptor Dysfunction and Dendritic Spine Loss through mGluR1 and AKAP150-Anchored Calcineurin Signaling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  3. Adam, amigo, brain, and K channel.Biophysical reviews · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Satoshi FujiiDepartment of Physiology, Yamagata University School of Medicine, Yamagata 990-9585, Japan.
Yoshihiko YamazakiDepartment of Physiology, Yamagata University School of Medicine, Yamagata 990-9585, Japan.
Jun-Ichi GotoDepartment of Physiology, Yamagata University School of Medicine, Yamagata 990-9585, Japan.
Hiroki FujiwaraDepartment of Physiology, Yamagata University School of Medicine, Yamagata 990-9585, Japan.
Katsuhiko MikoshibaLaboratory for Developmental Neurobiology, Riken Brain Science Institute, Wako, Saitama 351-0198, Japan.
Yamagata University · JPRIKEN Center for Brain Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In CA1 neurons of guinea pig hippocampal slices, long-term potentiation (LTP) was induced in field excitatory postsynaptic potentials (EPSPs) or population spikes (PSs) by the delivery of high-frequency stimulation (HFS, 100 pulses at 100 Hz) to CA1 synapses, and was reversed by the delivery of a train of low-frequency stimulation (LFS, 1000 pulses at 2 Hz) at 30 min after HFS (depotentiation), and this effect was inhibited when test synaptic stimulation was halted for a 19-min period after HFS or for a 20-min period after LFS or applied over the same time period in the presence of an antagonist of N-methyl-D-aspartate receptors (NMDARs), group I metabotropic glutamate receptors (mGluRs), or inositol 1, 4, 5-trisphosphate receptors (IP

Indexed as

AnimalsCA1 Region, HippocampalCalcineurinCalcineurin InhibitorsCalcium-Calmodulin-Dependent Protein Kinase Type 2Electric StimulationExcitatory Postsynaptic PotentialsGuinea PigsInositol 1,4,5-Trisphosphate ReceptorsLong-Term PotentiationLong-Term Synaptic DepressionMaleReceptors, Metabotropic GlutamateReceptors, N-Methyl-D-AspartateTime FactorsCalcineurinCalcineurin InhibitorsCalcium-Calmodulin-Dependent Protein Kinase Type 2Inositol 1,4,5-Trisphosphate Receptorsmetabotropic glutamate receptor type 1Receptors, Metabotropic GlutamateReceptors, N-Methyl-D-Aspartate

Identifiers

PMID31949037
PMCPMC6970427
OpenAlexW2999409340

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.