ArticleSchizophrenia research2020
Neighborhood-level predictors of age at onset and duration of untreated psychosis in first-episode psychotic disorders.
Article in Schizophrenia research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Social Fragmentation and Schizophrenia: A Systematic Review.The Journal of clinical psychiatry · 2021Pooled it
- The associations between migrant status and ethnicity and the identification of individuals at ultra-high risk for psychosis and transition to psychosis: a systematic review.Social psychiatry and psychiatric epidemiology · 2021Pooled it
- Environmental Exposures and Computational Mechanisms in Psychosis Risk: Insights from a Multi-Site Cohort.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Neighborhood Characteristics and Social Functioning: Exploring Shared and Distinct Psychosocial Pathways Among Individuals at Clinical High-Risk for Psychosis.Schizophrenia bulletin · 2026Article
- Neighborhood Characteristics and Psychosis Risk Across Development.Schizophrenia research · 2026Article
- Neighborhood social fragmentation and cerebello-thalamo-cortical connectivity in youth at clinical high-risk for psychosis and healthy comparisons.Brain and environment · 2026Article
- Food Insecurity, Neighborhood Disorder, and Homelessness among People with Serious Mental Illness.Community mental health journal · 2026Article
- Associations Between Genetic Risk, Physical Activities, and Distressing Psychotic-like Experiences.Schizophrenia bulletin · 2026Article
- Neighborhood-level social determinants of suicidality in youth with schizophrenia: An EHR-based study.Schizophrenia research · 2025Article
- The role of childhood social fragmentation and perceived discrimination on maladaptive core schemas later in life among young adults at clinical high risk for psychosis and healthy comparisons.Schizophrenia research · 2025Article
- Comprehensive spatial distribution of patients with first-episode psychosis (FEP) and its relation to socio-economic factors.Social psychiatry and psychiatric epidemiology · 2025Article
- Developmental perspectives on the origins of psychotic disorders: The need for a transdiagnostic approach.Development and psychopathology · 2024Review
- The association between neighborhood-level social fragmentation and distressing psychotic-like experiences in early adolescence: the moderating role of close friends.Psychological medicine · 2024Article
- Exploring causal mechanisms of psychosis risk.Neuroscience and biobehavioral reviews · 2024Review
- Aspects of Area Deprivation Index in Relation to Hippocampal Volume Among Children.JAMA network open · 2024Article
- Reorienting the focus from an individual to a community-level lens to improve the pathways through care for early psychosis in the United States.SSM. Mental health · 2023Article
- Urbanicity and psychotic disorders: Facts and hypotheses.Dialogues in clinical neuroscience · 2023Review
- Associations Between Childhood Area-Level Social Fragmentation, Maladaptation to School, and Social Functioning Among Healthy Youth and Those at Clinical High Risk for Psychosis.Schizophrenia bulletin · 2023Article
- Environmental resource reductions predict greater severity of negative symptoms in schizophrenia.Schizophrenia research · 2023Article
- Residential instability during adolescence predicts earlier age at onset of psychosis: The moderating role of extraversion.Early intervention in psychiatry · 2023Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveRecent years have witnessed growing interest in the role of the social environment in the development and outcomes of schizophrenia. We investigated whether neighborhood characteristics are associated with two important prognostic factors in early-course psychosis, age at onset of psychosis (AOP) and duration of untreated psychosis (DUP).
methodsData were collected from patients admitted to the hospital for first-episode schizophrenia-spectrum disorder. We collected data on perceived neighborhood disorder during childhood/adolescence and extracted data on 13 neighborhood characteristics from the American Community Survey based upon individual addresses. Four neighborhood-level factors were derived from factor analysis. Multiple logistic regression analyses assessed the association between specific neighborhood characteristics and the two prognostic factors (earlier AOP and longer DUP) in early-course psychosis.
results143 participants had valid addresses geo-coded. Neighborhood-level residential instability was associated with an earlier AOP (OR = 1.760; p = 0.022) even after controlling for known risk factors (OR = 2.026; p = 0.020) and also after controlling for individual-level residential instability (OR = 1.917; p = 0.037). The general socioeconomic status neighborhood factor (OR = 1.119; p = 0.019) and perceived neighborhood disorder (OR = 1.075; p = 0.005) were associated with a longer DUP. But only perceived neighborhood disorder (OR = 1.146; p = 0.011) remained significant, and general socioeconomic status was close to significant (OR = 1.215; p = 0.062), after controlling for individual-level predictors and socioeconomic status.
conclusionsThis study found evidence that neighborhood-level characteristics (in this case, residential instability) may be associated with earlier AOP, and perceptions of neighborhood disorder are associated with a longer treatment delay. Socioenvironmental factors should be more consistently considered going forward in research on early psychotic disorders.
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