Evidence map›Paper›PMID 31948523›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2020

[Risk factors for cow's milk protein allergy in infants: a multicenter survey].

Ji-Yong Zhang, Shao-Ming Zhou, Shao-Hua Wang, Feng-Xuan Sui, Wu-Hong Gao, Qing Liu, Hua-Bo Cai, Hong-Ying Jiang, Wei-Yan Li, Li-Ting Wang and 6 more

Abstract read
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. [Risk factors for cow's milk protein allergy in infants: a multicenter prospective nested case-control study].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
  2. [Association of pregnancy factors with cow's milk protein allergy in infants].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2024
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ji-Yong ZhangDepartment of Pediatrics, Shenzhen Maternity and Child Healthcare Hospital, Shenzhen, Guangdong 518017, China. zymdoctor2006@126.com.
Shao-Ming Zhou
Shao-Hua Wang
Feng-Xuan Sui
Wu-Hong Gao
Qing Liu
Hua-Bo Cai
Hong-Ying Jiang
Wei-Yan Li
Li-Ting Wang
Li Li
Wei Zhao
Jing Ying
Qian-Zhen Wu
Bi-Xia Weng
Yong-Mei Zeng

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the risk factors for cow's milk protein allergy (CMPA) among infants through a multicenter clinical study.

methodsA total of 1 829 infants, aged 1-12 months, who attended the outpatient service of the pediatric department in six hospitals in Shenzhen, China from June 2016 to May 2017 were enrolled as subjects. A questionnaire survey was performed to screen out suspected cases of CMPA. Food avoidance and oral food challenge tests were used to make a confirmed diagnosis of CMPA CMPA. A multivariate logistic regression analysis was used to investigate the risk factors for CMPA.

resultsAmong the 1 829 infants, 82 (4.48%) were diagnosed with CMPA. The multivariate logistic regression analysis showed that maternal food allergy (OR=4.91, 95%CI: 2.24-10.76, P<0.05), antibiotic exposure during pregnancy (OR=3.18, 95%CI: 1.32-7.65, P<0.05), and the introduction of complementary food at an age of <4 months (OR=3.55, 95%CI: 1.52-8.27, P<0.05) were risk factors for CMPA, while exclusive breastfeeding (OR=0.21, 95%CI: 0.08-0.58, P<0.05) and the introduction of complementary food at an age of >6 months (OR=0.38, 95%CI: 0.17-0.86, P<0.05) were protective factors.

conclusionsThe introduction of complementary food at an age of <4 months, maternal food allergy, and antibiotic exposure during pregnancy are risk factors for CMPA in infants.

Indexed as

Milk HypersensitivityAnimalsCattleChinaFemaleHumansInfantMilk ProteinsPregnancyRisk FactorsSurveys and QuestionnairesMilk Proteins

Identifiers

PMID31948523
PMCPMC7389720

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.