ArticleBMC research notes2020
Association of the leptin receptor Q223R (rs1137101) polymorphism with obesity measures in Sri Lankans.
Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 34 citations in OpenAlex.
- Genetic variability in the leptin-melanocortin pathway and its role in weight loss.Molecular metabolism · 2026Review
- Pancreatic Exocrine Insufficiency Is Surprisingly Common.Integrative medicine (Encinitas, Calif.) · 2026Article
- Insights into the molecular and genetic role of obesity in breast cancer pathogenesis.Cancer biology & therapy · 2025Review
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- The effect ofHeliyon · 2024Article
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- Using machine learning to identify gene interaction networks associated with breast cancer.BMC cancer · 2022Article
- Association of rs1137101 with hypertension and type 2 diabetes mellitus of Mongolian and Han Chinese.World journal of diabetes · 2022Article
- Association of Leptin Receptor Q223R Gene Polymorphism and Breast Cancer Patients: A Case Control Study.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Associations ofGenes · 2021Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveThe role of genetic factors in the development of obesity is largely unreported in Sri Lankans. The Q223R (rs1137101) single nucleotide polymorphism (SNP) of the leptin receptor (LEPR) gene has been associated with obesity measures in various ethnicities. We investigated the association of the Q223R polymorphism with obesity related anthropometric measures and biochemical parameters fasting blood glucose and lipid profile in a sample of 530 Sri Lankan adult subjects (age 18-70 years) representing both urban and rural areas of residence.
resultsThe LEPR Q223R variant G allele frequency was 0.54. The polymorphism was associated with body mass index (p = 0.04) and waist circumference (p = 0.02) measures in overweight and obese (BMI ≥ 25 kgm
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