Evidence map›Paper›PMID 31948120›Full record

ArticleNanomaterials (Basel, Switzerland)2020

Covalent Immobilization of β-Glucosidase into Mesoporous Silica Nanoparticles from Anhydrous Acetone Enhances Its Catalytic Performance.

Filomena Sannino, Aniello Costantini, Francesco Ruffo, Antonio Aronne, Virginia Venezia, Valeria Califano

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
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  3. Review
  4. Application of Immobilized β-Glucosidase fromIndian journal of microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Filomena SanninoDepartment of Agricultural Sciences, Università degli Studi di Napoli Federico II, Via Università 100, 80055 Portici (Na), Italy.
Aniello CostantiniDepartment of Chemical Engineering, Materials and Industrial Production, Università degli Studi di Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy.
Francesco RuffoDepartment of Chemical Science, Università degli Studi di Napoli Federico II, Complesso Universitario di Monte S. Angelo via Cintia, 80126 Napoli, Italy.
Antonio AronneDepartment of Chemical Engineering, Materials and Industrial Production, Università degli Studi di Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy.
Virginia VeneziaDepartment of Chemical Engineering, Materials and Industrial Production, Università degli Studi di Napoli Federico II, P.le Tecchio 80, 80125 Napoli, Italy.
Valeria CalifanoIstituto Motori-CNR, via G. Marconi 4, 80125 Napoli, Italy.
University of Naples Federico II · ITIstituto Motori · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An immobilization protocol of a model enzyme into silica nanoparticles was applied. This protocol exploited the use of the bifunctional molecule triethoxysilylpropylisocyanate (TEPI) for covalent binding through a linker of suitable length. The enzyme β-glucosidase (BG) was anchored onto wrinkled silica nanoparticles (WSNs). BG represents a bottleneck in the conversion of lignocellulosic biomass into biofuels through cellulose hydrolysis and fermentation. The key aspect of the procedure was the use of an organic solvent (anhydrous acetone) in which the enzyme was not soluble. This aimed to restrict its conformational changes and thus preserve its native structure. This approach led to a biocatalyst with improved thermal stability, characterized by high immobilization efficiency and yield. It was found that the apparent

Indexed as

covalent immobilizationmesoporous silica nanoparticlesβ-glucosidase

Identifiers

PMID31948120
PMCPMC7022324
OpenAlexW2998533407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.