Evidence map›Paper›PMID 31948091›Full record

Trial reportCells2020

CD276-Positive Circulating Endothelial Cells Do Not Predict Response to Systemic Therapy in Advanced Colorectal Cancer.

Elske C Gootjes, Jaco Kraan, Tineke E Buffart, Lotte Bakkerus, Barbara M Zonderhuis, Cornelis Verhoef, Henk M W Verheul, And Stefan Sleijfer

Open access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Elske C GootjesDepartment of Medical Oncology VUmc, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam 1081 HV, The Netherlands.
Jaco KraanDepartment of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam 3015 GD, The Netherlands.
Tineke E BuffartDepartment of Medical Oncology VUmc, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam 1081 HV, The Netherlands.
Lotte BakkerusDepartment of Medical Oncology VUmc, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam 1081 HV, The Netherlands.
Barbara M ZonderhuisDepartment of Surgical Oncology VUmc, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam 1081 HV, The Netherlands.
Cornelis VerhoefDepartment of Surgical Oncology, Erasmus MC-Cancer Institute, Rotterdam 3015 GD, The Netherlands.
Henk M W VerheulDepartment of Medical Oncology VUmc, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam 1081 HV, The Netherlands.
And Stefan SleijferDepartment of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam 3015 GD, The Netherlands.
Erasmus MC Cancer Institute · NLAmsterdam University Medical Centers · NLThe Netherlands Cancer Institute · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD276 can discriminate between tumor derived and normal CECs (circulating endothelial cells). We evaluated whether CD276

Indexed as

Area Under CurveB7 AntigensColorectal NeoplasmsEndothelial CellsHumansNeoplasm StagingB7 AntigensCD276 protein, humanbevacizumabCD276+chemotherapycirculating endothelial cellscolorectal cancer

Identifiers

PMID31948091
PMCPMC7016770
OpenAlexW2997930329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.