Evidence map›Paper›PMID 31948023›Full record

ArticlePolymers2020

Gamma Ray-Induced Polymerization and Cross-Linking for Optimization of PPy/PVP Hydrogel as Biomaterial.

Jin-Oh Jeong, Jong-Seok Park, Young-Ah Kim, Su-Jin Yang, Sung-In Jeong, Jae-Young Lee, Youn-Mook Lim

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jin-Oh JeongAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongup-si, Jeollabuk-do 56212, Korea.
Jong-Seok ParkAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongup-si, Jeollabuk-do 56212, Korea.ORCID 0000-0002-4389-1590
Young-Ah KimAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongup-si, Jeollabuk-do 56212, Korea.
Su-Jin YangAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongup-si, Jeollabuk-do 56212, Korea.
Sung-In JeongAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongup-si, Jeollabuk-do 56212, Korea.
Jae-Young LeeSchool of Materials Science and Engineering, Gwangju Institute of Science and Technology, Gwangju 61005, Korea.ORCID 0000-0003-4493-2494
Youn-Mook LimAdvanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongup-si, Jeollabuk-do 56212, Korea.
Korea Atomic Energy Research Institute · KRGwangju Institute of Science and Technology · KR

Funding

National Research Foundation of Korea NRF-2017M2A2A6A02018535
6 · The paper itself

Abstract

Conducting polymer (CP)-based hydrogels exhibit the behaviors of bending or contraction/relaxation due to electrical stimulation. They are similar in some ways to biological organs and have advantages regarding manipulation and miniaturization. Thus, these hydrogels have attracted considerable interest for biomedical applications. In this study, we prepared PPy/PVP hydrogel with different concentrations and content through polymerization and cross-linking induced by gamma-ray irradiation at 25 kGy to optimize the mechanical properties of the resulting PPy/PVP hydrogel. Optimization of the PPy/PVP hydrogel was confirmed by characterization using scanning electron microscopy, gel fraction, swelling ratio, and Fourier transform infrared spectroscopy. In addition, we assessed live-cell viability using live/dead assay and CCK-8 assay, and found good cell viability regardless of the concentration and content of Py/pTS. The conductivity of PPy/PVP hydrogel was at least 13 mS/cm. The mechanical properties of PPy/PVP hydrogel are important factors in their application for biomaterials. It was found that 0.15PPy/PVP20 (51.96 ± 6.12 kPa) exhibited better compressive strength than the other samples for use in CP-based hydrogels. Therefore, it was concluded that gamma rays can be used to optimize PPy/PVP hydrogel and that biomedical applications of CP-based hydrogels will be possible.

Indexed as

crosslinkinggamma rayhydrogelpolypyrrolepolyvinylpyrrolidone

Identifiers

PMID31948023
PMCPMC7023038
OpenAlexW2997443690

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.