Evidence map›Paper›PMID 31947934›Full record

ArticleMolecules (Basel, Switzerland)2020

Assessing Amphiphilic ABAB Zn(II) Phthalocyanines with Enhanced Photosensitization Abilities in In Vitro Photodynamic Therapy Studies Against Cancer.

Miguel Á Revuelta-Maza, Marta Mascaraque, Patricia González-Jiménez, Arturo González-Camuñas, Santi Nonell, Ángeles Juarranz, Gema de la Torre, Tomás Torres

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Miguel Á Revuelta-MazaDepartments of Organic Chemistry and Biology, Universidad Autónoma de Madrid. C/Francisco Tomás y Valiente 7, 28049 Madrid, Spain.
Marta MascaraqueDepartments of Organic Chemistry and Biology, Universidad Autónoma de Madrid. C/Francisco Tomás y Valiente 7, 28049 Madrid, Spain.ORCID 0000-0002-9677-921X
Patricia González-JiménezDepartments of Organic Chemistry and Biology, Universidad Autónoma de Madrid. C/Francisco Tomás y Valiente 7, 28049 Madrid, Spain.
Arturo González-CamuñasDepartments of Organic Chemistry and Biology, Universidad Autónoma de Madrid. C/Francisco Tomás y Valiente 7, 28049 Madrid, Spain.
Santi NonellInstitut Químic de Sarrià. Universitat Ramon Llull, 08017 Barcelona, Spain.ORCID 0000-0002-8900-5291
Ángeles JuarranzDepartments of Organic Chemistry and Biology, Universidad Autónoma de Madrid. C/Francisco Tomás y Valiente 7, 28049 Madrid, Spain.ORCID 0000-0002-6574-2887
Gema de la TorreDepartments of Organic Chemistry and Biology, Universidad Autónoma de Madrid. C/Francisco Tomás y Valiente 7, 28049 Madrid, Spain.
Tomás TorresDepartments of Organic Chemistry and Biology, Universidad Autónoma de Madrid. C/Francisco Tomás y Valiente 7, 28049 Madrid, Spain.ORCID 0000-0001-9335-6935

Funding

Ministerio de Economía, Industria y Competitividad, Gobierno de España CTQ2017-85393-P and CTQ2016-78454-C2-1-R
6 · The paper itself

Abstract

We have previously demonstrated that singlet oxygen photosensitization abilities of Zn(II) phthalocyanines (Zn(II)Pcs) are enhanced through α-functionalization with bulky fluorinated substituents (i.e., bis(trifluoromethyl)phenyl units) at facing positions of ABAB Zn(II)Pcs, where A and B refer to differently functionalized isoindoles. In this work, we have prepared the Zn(II)Pc

Indexed as

Cell Line, TumorHeLa CellsHumansHydrophobic and Hydrophilic InteractionsIndolesIsoindolesPhotochemotherapyPhotosensitizing AgentsPolyethylene GlycolsSinglet OxygenSolubilityIndolesIsoindolesPhotosensitizing AgentsphthalocyaninePolyethylene GlycolsSinglet Oxygentriethylene glycolABABamphiphilicHeLaphotodynamic therapySCC-13Zn(II) phthalocyanines

Identifiers

PMID31947934
PMCPMC6983099

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.