Evidence map›Paper›PMID 31947911›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Performance Assessment of Software to Detect and Assist Prescribers with Antimicrobial Drug Interactions: Are all of them Created Equal?

Elena Morte-Romea, Pilar Luque-Gómez, Mercedes Arenere-Mendoza, Jose Luis Sierra-Monzón, Ana Camón Pueyo, Galadriel Pellejero Sagastizabal, Guillermo Verdejo Muñoz, David Sánchez Fabra, José Ramón Paño-Pardo

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elena Morte-RomeaInfectious Diseases Service, Hospital Clínico Universitario "Lozano Blesa", 50009 Zaragoza, Spain.ORCID 0000-0001-9262-2461
Pilar Luque-GómezInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.
Mercedes Arenere-MendozaInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.
Jose Luis Sierra-MonzónInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.
Ana Camón PueyoInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.ORCID 0000-0001-9924-4037
Galadriel Pellejero SagastizabalInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.
Guillermo Verdejo MuñozInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.
David Sánchez FabraInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.
José Ramón Paño-PardoInfectious Diseases Service, Hospital Clínico Universitario "Lozano Blesa", 50009 Zaragoza, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDetecting and managing antimicrobial drug interactions (ADIs) is one of the facets of prudent antimicrobial prescribing. Our aim is to compare the capability of several electronic drug-drug interaction (DDI) checkers to detect and report ADIs.

methodsSix electronic DDI checking platforms were evaluated: Drugs.com

resultsThe electronic DDI checkers did not detect a significant proportion of the ADI assessed. The overall performance score ranged between 4.4 (Medimecum) and 8.8 (Drugs.com). Drugs.com was the highest ranked platform in four out of five dimensions (sensitivity, effect, mechanism, and recommended action).

conclusionsThere is significant variability in the performance of the available platforms in detecting and assessing ADI. Although some ADI checkers have proven to be very accurate, others missed almost half of the explored interactions.

Indexed as

antimicrobialantimicrobial drug interactionsantimicrobial stewardshippharmacy

Identifiers

PMID31947911
PMCPMC7167986

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.