Evidence map›Paper›PMID 31947825›Full record

ArticleViruses2020

Novel Approach for Insertion of Heterologous Sequences into Full-Length ZIKV Genome Results in Superior Level of Gene Expression and Insert Stability.

Evgeniya Volkova, Konstantin A Tsetsarkin, Emilia Sippert, Felipe Assis, Guangping Liu, Maria Rios, Alexander G Pletnev

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Evgeniya VolkovaOffice of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Silver Spring, MD 20993, USA.ORCID 0000-0002-3564-3423
Konstantin A TsetsarkinLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
Emilia SippertOffice of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Silver Spring, MD 20993, USA.ORCID 0000-0002-6341-3879
Felipe AssisOffice of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Silver Spring, MD 20993, USA.
Guangping LiuLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
Maria RiosOffice of Blood Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Silver Spring, MD 20993, USA.
Alexander G PletnevLaboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD 20892, USA.
Center for Biologics Evaluation and Research · USNational Institutes of Health · US

Funding

Development Of New Approaches To Vaccines Against TBEV and West Nile VirusZIAAI000637 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI PLETNEV, ALEXANDER · 2009 to 2022
$19.1M
6 · The paper itself

Abstract

Zika virus (ZIKV) emerged in the Americas in 2015, presenting unique challenges to public health. Unlike other arboviruses of the

Indexed as

AnimalsAntigens, HeterophileCapsid ProteinsChlorocebus aethiopsCloning, MolecularDNA Transposable ElementsGene ExpressionGenes, ViralGenome, ViralGreen Fluorescent ProteinsHumansReverse GeneticsVero CellsVirus ReplicationZika VirusAntigens, HeterophileCapsid ProteinsDNA Transposable ElementsGreen Fluorescent Proteinsbioluminescenceflavivirusesheterologous gene expressionreverse geneticsZika virus

Identifiers

PMID31947825
PMCPMC7019263
OpenAlexW2998075133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.