Evidence map›Paper›PMID 31947648›Full record

ArticleInternational journal of molecular sciences2020

Site-Specific Expression Pattern of PIWI-Interacting RNA in Skin and Oral Mucosal Wound Healing.

Lin Chen, Zujian Chen, Alyne Simões, Xinming Wu, Yang Dai, Luisa A DiPietro, Xiaofeng Zhou

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lin ChenCenter for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Zujian ChenDepartment of Periodontics, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Alyne SimõesCenter for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Xinming WuDepartment of Periodontics, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Yang DaiDepartment of Bioengineering, College of Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA.
Luisa A DiPietroCenter for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA.
Xiaofeng ZhouCenter for Wound Healing and Tissue Regeneration, College of Dentistry, University of Illinois at Chicago, Chicago, IL 60612, USA.
University of Illinois Chicago · USUniversidade de São Paulo · BR

Funding

ANGIOGENESIS IN WOUND REPAIRR01GM050875 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DIPIETRO, LUISA A · 1999 to 2020
$6.6M
MicroRNA regulation of the injury response in oral mucosaR21DE025926 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DIPIETRO, LUISA A, ZHOU, XIAOFENG · 2016 to 2017
$440k
NIDCR NIH HHS R21 DE025926NIDCR NIH HHS R21DE025926NIGMS NIH HHS R01 GM050875NIGMS NIH HHS R01GM50875
6 · The paper itself

Abstract

The oral mucosa exhibits exceptional healing capability when compared to skin. Recent studies suggest that intrinsic differences in coding genes and regulatory small non-coding RNA (sncRNA) genes (e.g., microRNAs) may underlie the exceptional healing that occurs in the oral mucosa. Here, we investigate the role of a novel class of sncRNA-Piwi-interacting RNA (piRNA)-in the tissue-specific differential response to injury. An abundance of piRNAs was detected in both skin and oral mucosal epithelium during wound healing. The expression of

Indexed as

Gene Expression RegulationRNA, Small InterferingAnimalsComputational BiologyFemaleGene Expression ProfilingMiceMouth MucosaSkinTranscriptomeWound HealingRNA, Small Interferingoral mucosapiRNAPIWI geneskinwound healing

Identifiers

PMID31947648
PMCPMC7013508
OpenAlexW2999252531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.