ReviewMolecules (Basel, Switzerland)2020
Ozonated Oils as Antimicrobial Systems in Topical Applications. Their Characterization, Current Applications, and Advances in Improved Delivery Techniques.
Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07728422 (Effects of Ozone Therapy Modalities on Biochemical Markers of Muscle Damage Following Eccentric Exercise), which is not on this map. Cited by 71 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Ozone Therapy Modalities on Biochemical Markers of Muscle Damage Following Eccentric Exercise
Who cites it
71 citing papers in PubMed.
- Effects of topical ozonated olive oil on lipid profile, quality of life, wound healing and glycemic control in patients with diabetic foot ulcers: a randomized controlled trial.Lipids in health and disease · 2025Trial
- Comparison of HDL-Associated Antioxidant Activities and Anti-Inflammatory Effect Between Ozonated Sunflower Oil (OSO) and Ozonated Olive Oil (OOO) Under Carboxymethyllysine-Induced Acute Phase in Zebrafish Adults and Embryos.Antioxidants (Basel, Switzerland) · 2026Article
- The Effect of Ozone Therapy on Psoriasis.Clinical case reports · 2026Article
- Evaluation of a Commercial Ozonated Olive Oil Product (800 mEq OPathogens (Basel, Switzerland) · 2026Article
- Application of Coltosol F with a cotton-spacer technique for endodontic temporization: a clinical retrospective study.BMC oral health · 2026Article
- Endometrial gland remodeling and preserved luminal ultrastructure in postpartum cows infused with ozonated sunflower oil.Animal reproduction · 2026Article
- Tolerability of 0.5% Liposomal Ozonated Oil Versus 0.6% Povidone-Iodine in Antiseptic Prophylaxis for Intravitreal Injections.Ophthalmology and therapy · 2026Article
- Exploratory Pilot Study on the Tolerability and Ocular Surface Effects of Liposomal Ozonated Oil Compared with Standard Prophylaxis in Cataract Surgery. The CAREST Study.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Oxygen-Based Adjunct Therapies in Periodontitis: A Systematic Review and Meta-Analysis Within the Framework of Hypoxia and Inflammation.Biomedicines · 2025Review
- Ozone-Mediated Modulation of Green Tea Extract Enhances Bioactive Compounds and Therapeutic Potential Relevant to Human Health.Pharmaceuticals (Basel, Switzerland) · 2025Article
- The Rising Importance of Antiseptics in Ophthalmology: From Endophthalmitis Prevention to Treatment of Ocular Infections.Ophthalmology and therapy · 2025Review
- Ozone-Assisted Green Upgrading ofFoods (Basel, Switzerland) · 2025Article
- Ozonized Sunflower Oil: Standardization and Mechanisms of the Antimicrobial Effect.International journal of molecular sciences · 2025Article
- Physico-Chemical and Antimicrobial Evaluation of Ozonated Olive Oil Produced with a Medical-Grade Generator for Veterinary Purposes.Microorganisms · 2025Article
- Nanocarriers for Medical Ozone Delivery: A New Therapeutic Strategy.Nanomaterials (Basel, Switzerland) · 2025Review
- Ozone-modified properties of pumpkin seed oil as anti-H. pylori, anticancer, anti-diabetic and anti-obesity agent.Scientific reports · 2025Article
- Topical ozone application for severe acne with serological evidence of prior varicella-zoster infection after unsuccessful antibiotic and corticosteroid treatment: a case report.Journal of medical case reports · 2025Article
- Phytochemical characterization of peanut oil and its ozonized form to explore biological activities in vitro.AMB Express · 2025Article
- Ozonated Sunflower Oil Stimulates the Local Antioxidant System and Helps Meglumine Antimoniate to Ameliorate Cutaneous Leishmaniasis Lesions.ACS omega · 2025Article
- Effects of Ozonation on the Physicochemical Properties and Antimicrobial Activity of Virgin and Pomace Olive Oils.Journal of food science · 2025Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The search for a wide spectrum of antimicrobial agents that can avoid resistance while maintaining reasonable side effects has led to ozonated oils experiencing an increase in scientific interest and clinical applications. The treatment of vegetable oils with ozone leads to the creation of a reservoir of ozone that slowly releases into the skin thanks to the fact that ozone can be held as ozonides of unsaturated fatty acids. Interest in the use of ozonated oils has meant that several ozonated-vegetable-oil-containing products have been commercialized as cosmetic and pharmaceutical agents, and in innovative textile products with antibacterial activity. New approaches to the delivery of ozonated oils have very recently appeared in an attempt to improve their characteristics and reduce drawbacks, such as an unpleasant odor, high viscosity and undesired effects on skin, including irritation and rashes. The present review focuses on the current status of delivery agents that use ozonated oils as antimicrobial agents in topical (dermal, skin, and soft tissues) treatments. Challenges and future opportunities for these delivery systems will also be discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.