ArticleAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2019
A Scalable Random Access Micro-traps Array for Formation, Selective Retrieval and Capturing of Individual Droplets.
Article in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Formation, selective retrieval and capturing of individual droplets are key operational capabilities needed for a broad range of droplet microfluidic applications. The membrane displacement trap (MDT) element gives a robust method for uniform discretization and controllable manipulation of aqueous droplets using an enclosed micro-well covered by an elastomer membrane. This capability can be scaled up by combining the modular elements with a system design that requires a minimal number of signal inputs. Incorporation of MDT elements with a pneumatically-controllable multiplexer system can lead to a scalable random access MDT array platform for liquid discretization and selective manipulation. Herein, we report the design and development of a programmable droplet microfluidic platform for liquid sampling and selectively handling up to 32 individual droplets using 10 pneumatic signal inputs. The multiplexer system can logarithmically scale up capacity of the MDT array platform, making it possible to manipulate hundreds droplets.
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