Evidence map›Paper›PMID 31945376›Full record

ArticleJournal of molecular biology2020

A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.

Sweta Vangaveti, William A Cantara, Jessica L Spears, Hasan DeMirci, Frank V Murphy, Sri V Ranganathan, Kathryn L Sarachan, Paul F Agris

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Nonenzymatic RNA copying with a potentially primordial genetic alphabet.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Review
  3. Mapping the tRNA modification landscape ofFrontiers in microbiology · 2024
    Article
  4. Epitranscriptome: Review of Top 25 Most-Studied RNA Modifications.International journal of molecular sciences · 2022
    Review
  5. Article
  6. Article
  7. Review
  8. Synthesis and Metabolic Fate of 4-Methylthiouridine in Bacterial tRNA.Chembiochem : a European journal of chemical biology · 2020
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sweta VangavetiThe RNA Institute, University at Albany-SUNY, 1400 Washington Ave., Albany, NY, 12222, USA.
William A CantaraDepartment of Biological Sciences, University at Albany-SUNY, 1400 Washington Ave., Albany, NY, 12222, USA.
Jessica L SpearsDepartment of Biological Sciences, University at Albany-SUNY, 1400 Washington Ave., Albany, NY, 12222, USA.
Hasan DeMirciPULSE Institute, Stanford University, 2575 Sand Hill Road, MS 59, Menlo Park, CA, 94025, USA; Department of Molecular Biology and Genetics, Koc University, Rumelifeneri yolu, Sariyer, Istanbul, 34450, Turkey.
Frank V MurphyArgonne National Laboratories, NE-CAT/Cornell University, 9700 S. Cass Avenue, Lemont, IL, 60439, USA.
Sri V RanganathanThe RNA Institute, University at Albany-SUNY, 1400 Washington Ave., Albany, NY, 12222, USA.
Kathryn L SarachanDepartment of Biological Sciences, University at Albany-SUNY, 1400 Washington Ave., Albany, NY, 12222, USA; The RNA Institute, University at Albany-SUNY, 1400 Washington Ave., Albany, NY, 12222, USA. Electronic address: kathryn.sarachan@wilson.edu.
Paul F AgrisDepartment of Biological Sciences, University at Albany-SUNY, 1400 Washington Ave., Albany, NY, 12222, USA; The RNA Institute, University at Albany-SUNY, 1400 Washington Ave., Albany, NY, 12222, USA. Electronic address: paul.agris@duke.edu.
University at Albany, State University of New York · USCornell University · USStanford University · US

Funding

User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI Nozomi Ando, J Christopher Fromme · 2018 to 2026
$34.2M
RNA modification: Structure and MechanismR01GM110588 · NIGMS · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI SWAIRJO, MANAL A · 2014 to 2024
$3.9M
TRANSFER RNA STRUCTURE DURING PROTEIN SYNTHESISR01GM023037 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI AGRIS, PAUL F · 1985 to 2010
$1.3M
NIGMS NIH HHS P30 GM124165NIGMS NIH HHS R01 GM023037NIGMS NIH HHS R01 GM110588
6 · The paper itself

Abstract

Three of six arginine codons (CGU, CGC, and CGA) are decoded by two Escherichia coli tRNA

Indexed as

CodonComputational BiologyCrystallography, X-RayCytidineInosineNucleosidesRNARNA, TransferSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsThermodynamics2-thiocytidineCodonCytidineInosineNucleosidesRNARNA, TransferSaccharomyces cerevisiae Proteinsmodified nucleosidesRNA functionRNA structuretRNAwobble decoding

Identifiers

PMID31945376
PMCPMC7102896
OpenAlexW2999595838

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.