Evidence map›Paper›PMID 31945264›Full record

ArticleFEBS open bio2020

Crystal structure of botulinum neurotoxin subtype A3 cell binding domain in complex with GD1a co-receptor ganglioside.

Kyle S Gregory, Sai Man Liu, K Ravi Acharya

Open access · goldAbstract read
In one paragraph

Article in FEBS open bio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Crystal Structures of theInternational journal of molecular sciences · 2022
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Kyle S GregoryDepartment of Biology and Biochemistry, Claverton Down, University of Bath, UK.ORCID 0000-0001-5371-4283
Sai Man LiuIpsen Bioinnovation Limited, Abingdon, UK.ORCID 0000-0001-6359-0229
K Ravi AcharyaDepartment of Biology and Biochemistry, Claverton Down, University of Bath, UK.ORCID 0000-0002-3009-4058
University of Bath · GBIpsen (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Botulinum neurotoxins (BoNTs) are one of the most toxic proteins known to humans. Their molecular structure is comprised of three essential domains-a cell binding domain (H

Indexed as

Binding SitesBotulinum ToxinsBotulinum Toxins, Type ACarrier ProteinsCell MembraneCrystallography, X-RayGangliosidesHumansNeuronsProtein BindingProtein DomainsBotulinum ToxinsBotulinum Toxins, Type ACarrier Proteinsganglioside, GD1aGangliosidesbotulinum neurotoxincell binding domaincrystallographyganglioside bindingprotein structure

Identifiers

PMID31945264
PMCPMC7050238
OpenAlexW2998988007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.