Evidence map›Paper›PMID 31944881›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2020

Effects of inhaled fluticasone propionate on extrinsic tongue muscles in rats.

Christopher Setzke, Oleg Broytman, John A Russell, Natalie Morel, Michelle Sonsalla, Dudley W Lamming, Nadine P Connor, Mihaela Teodorescu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Sarcopenia of the longitudinal tongue muscles in rats.Respiratory physiology & neurobiology · 2024
    Article
  5. Tongue muscle contractile, fatigue, and fiber type properties in rats.Journal of applied physiology (Bethesda, Md. : 1985) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Christopher SetzkeDepartment of Medicine and University of Wisconsin, Madison, Wisconsin.
Oleg BroytmanDepartment of Medicine and University of Wisconsin, Madison, Wisconsin.
John A RussellDepartment of Surgery, University of Wisconsin, Madison, Wisconsin.
Natalie MorelDepartment of Medicine and University of Wisconsin, Madison, Wisconsin.
Michelle SonsallaDepartment of Medicine and University of Wisconsin, Madison, Wisconsin.
Dudley W LammingDepartment of Medicine and University of Wisconsin, Madison, Wisconsin.
Nadine P ConnorDepartment of Surgery, University of Wisconsin, Madison, Wisconsin.
Mihaela TeodorescuDepartment of Medicine and University of Wisconsin, Madison, Wisconsin.
University of Wisconsin–Madison · USWilliam S. Middleton Memorial Veterans Hospital · US

Funding

Lingual and Laryngeal Muscle PlasticityR01DC008149 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI CONNOR, NADINE P · 2007 to 2017
$4.5M
The regulation of health and longevity by branched-chain amino acidsR01AG056771 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Dudley William Lamming · 2018 to 2026
$3.1M
Bioenergetic Mechanisms of Tongue Muscle FatigueR01DC018071 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI CONNOR, NADINE P · 2019 to 2023
$2.5M
Treatment of Functional Deficits IN tongue muscles induced by radiation and chemoradiation treatmentR37CA225608 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI RUSSELL, JOHN A · 2018 to 2024
$2.4M
The regulation of health and longevity by branched-chain amino acidsRF1AG056771 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LAMMING, DUDLEY WILLIAM · 2023 to 2023
$2.1M
Comparative analysis of geroprotective interventions in established and novel mouse models of Alzheimer's diseaseR01AG062328 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LAMMING, DUDLEY WILLIAM, MERRINS, MATTHEW J. · 2018 to 2022
$2.0M
The regulation of health and longevity by branched-chain amino acidsR56AG056771 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LAMMING, DUDLEY WILLIAM · 2017 to 2017
$573k
Promoting metabolic health through the reduction of dietary branched chain amino acidsI01BX004031 · VA · WM S. MIDDLETON MEMORIAL VETERANS HOSP · PI LAMMING, DUDLEY WILLIAM · 2018 to 2022
–
BLRD VA I01 BX004031NCI NIH HHS R37 CA225608NIA NIH HHS R01 AG056771NIA NIH HHS R01 AG062328NIA NIH HHS R56 AG056771NIA NIH HHS RF1 AG056771NIDCD NIH HHS R01 DC008149NIDCD NIH HHS R01 DC018071
6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) is more common in patients with asthma, and inhaled corticosteroids may contribute to OSA pathogenesis in these patients. This study tested the effects of orally inhaled fluticasone propionate (FP) on extrinsic tongue muscles. Unanesthetized rats were treated with FP or placebo for 28 days. On

Indexed as

Hypoglossal NerveTongueAnimalsFacial MusclesFluticasoneHumansMuscle Fibers, SkeletalRatsFluticasoneasthmaextrinsic tonguefluticasone propionateinhaled corticosteroidsobstructive sleep apnea

Identifiers

PMID31944881
PMCPMC7099439
OpenAlexW3000577677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.