Evidence map›Paper›PMID 31944824›Full record

ArticleThe British journal of radiology2020

Proton minibeams-a springboard for physics, biology and clinical creativity.

F Avraham Dilmanian, Bhanu P Venkatesulu, Narayan Sahoo, Xiaodong Wu, Jessica R Nassimi, Steven Herchko, Jiade Lu, Bilikere S Dwarakanath, John G Eley, Sunil Krishnan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The British journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Proton therapy special feature: introductory editorial.The British journal of radiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

F Avraham DilmanianDepartments of Radiology, Health Sciences Center and Cancer Center, Stony Brook University, Stony Brook, NY, USA.
Bhanu P VenkatesuluDepartment of Experimental Radiation Oncology, Health Sciences Center and Cancer Center, Stony Brook University, Stony Brook, NY, USA.
Narayan SahooDepartments of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Xiaodong WuBiophysics Research Institute of America, Miami, FL, USA.
Jessica R NassimiDepartments of Radiology, Health Sciences Center and Cancer Center, Stony Brook University, Stony Brook, NY, USA.
Steven HerchkoDepartment of Radiation Oncology, Mayo Clinic Florida, Jacksonville, FL, USA.
Jiade LuDepartment of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai, China.
Bilikere S DwarakanathDepartment of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Shanghai, China.
John G EleyDepartment of Radiation Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
Sunil KrishnanDepartment of Radiation Oncology, Mayo Clinic Florida, Jacksonville, FL, USA.ORCID http://orcid.org/0000-0002-1340-4771

Funding

Proton minibeams: Overcoming proton beams’ inability to spare superficial tissuesR21CA191818 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DILMANIAN, F AVRAHAM, ELEY, JOHN G. · 2016 to 2017
$410k
NCI NIH HHS R21 CA191818
6 · The paper itself

Abstract

Proton minibeam therapy (PMBT) is a form of spatially fractionated radiotherapy wherein broad beam radiation is replaced with segmented minibeams-either parallel, planar minibeam arrays generated by a multislit collimator or scanned pencil beams that converge laterally at depth to create a uniform dose layer at the tumor. By doing so, the spatial pattern of entrance dose is considerably modified while still maintaining tumor dose and efficacy. Recent studies using computational modeling, phantom experiments,

Indexed as

CreativityAbsorption, RadiationAlgorithmsDose Fractionation, RadiationFeasibility StudiesHumansMonte Carlo MethodNeoplasmsOrgans at RiskOrgan Sparing TreatmentsProton TherapyRadiobiologyRadiometry

Identifiers

PMID31944824
PMCPMC7066973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.