ArticleAnalytical chemistry2020
Simultaneous Detection of Zinc and Its Pathway Metabolites Using MALDI MS Imaging of Prostate Tissue.
Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- Advances in spatial omics for the analysis of prostate cancer.Analytical and bioanalytical chemistry · 2026Review
- Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry.Nature reviews. Methods primers · 2026Article
- Spatial multi-omics identifies aggressive prostate cancer signatures highlighting pro-inflammatory chemokine activity in the tumor microenvironment.Nature communications · 2025Article
- Review
- Spatial integration of multi-omics data from serial sections using the novel Multi-Omics Imaging Integration Toolset.GigaScience · 2025Article
- A Simple and Rapid "Turn-On" Fluorescent Probe Based on Binuclear Schiff Base for ZnMolecules (Basel, Switzerland) · 2024Article
- Mass spectrometry imaging reveals flavor distribution in edible mushrooms.Journal of food science and technology · 2024Article
- Deciphering feedback regulation of prostaglandin F2α in blood stasis syndrome using nitrogen-doped porous transition metal carbides.Mikrochimica acta · 2024Article
- Review
- Workflow for High-throughput Screening of Enzyme Mutant Libraries Using Matrix-assisted Laser Desorption/Ionization Mass Spectrometry Analysis ofBio-protocol · 2023Article
- Mass spectrometry imaging for biosolids characterization to assess ecological or health risks before reuse.Nature communications · 2023Article
- Sample Preparation for Metabolite Detection in Mass Spectrometry Imaging.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Facets of ICP-MS and their potential in the medical sciences-Part 1: fundamentals, stand-alone and hyphenated techniques.Analytical and bioanalytical chemistry · 2022Review
- An optimized MALDI MSI protocol for spatial detection of tryptic peptides in fresh frozen prostate tissue.Proteomics · 2022Article
- A simple preparation protocol for shipping and storage of tissue sections for laser ablation-inductively coupled plasma-mass spectrometry imaging.Metallomics : integrated biometal science · 2022Article
- Zinc-containing Mohs' paste affects blood flow and angiogenesis suppression.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2021Article
- Reproducible Lipid Alterations in Patient-Derived Breast Cancer Xenograft FFPE Tissue Identified with MALDI MSI for Pre-Clinical and Clinical Application.Metabolites · 2021Article
- Removal of optimal cutting temperature (O.C.T.) compound from embedded tissue for MALDI imaging of lipids.Analytical and bioanalytical chemistry · 2021Article
- Spatial Segmentation of Mass Spectrometry Imaging Data by Combining Multivariate Clustering and Univariate Thresholding.Analytical chemistry · 2021Article
- Spatial differentiation of metabolism in prostate cancer tissue by MALDI-TOF MSI.Cancer & metabolism · 2021Article
Corrections and comments
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Authors and funding
14 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Levels of zinc, along with its mechanistically related metabolites citrate and aspartate, are widely reported as reduced in prostate cancer compared to healthy tissue and are therefore pointed out as potential cancer biomarkers. Previously, it has only been possible to analyze zinc and metabolites by separate detection methods. Through matrix-assisted laser desorption/ionization mass spectrometry imaging (MSI), we were for the first time able to demonstrate, in two different sample sets (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.