Evidence map›Paper›PMID 31944312›Full record

ReviewJournal of medical virology2020

Recent advances in the detection of respiratory virus infection in humans.

Naru Zhang, Lili Wang, Xiaoqian Deng, Ruiying Liang, Meng Su, Chen He, Lanfang Hu, Yudan Su, Jing Ren, Fei Yu and 2 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 246 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
246citing papers in PubMed, 3 pooled it
62.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

246 citing papers in PubMed, 3 syntheses or guidelines pooled it, 563 citations in OpenAlex.

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  20. The impact of COVID-19 pandemic on the etiological spectrum of respiratory infections in children.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article

186 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Naru ZhangDepartment of Clinical Medicine, School of Medicine, Zhejiang University City College, Hangzhou, China.
Lili WangState Key Laboratory of North China Crop Improvement and Regulation, Research Center of Chinese Jujube, Hebei Agricultural University, Baoding, China.
Xiaoqian DengState Key Laboratory of North China Crop Improvement and Regulation, College of Life and Science, Hebei Agricultural University, Baoding, China.
Ruiying LiangState Key Laboratory of North China Crop Improvement and Regulation, College of Life and Science, Hebei Agricultural University, Baoding, China.
Meng SuState Key Laboratory of North China Crop Improvement and Regulation, College of Life and Science, Hebei Agricultural University, Baoding, China.
Chen HeState Key Laboratory of North China Crop Improvement and Regulation, College of Life and Science, Hebei Agricultural University, Baoding, China.
Lanfang HuState Key Laboratory of North China Crop Improvement and Regulation, College of Life and Science, Hebei Agricultural University, Baoding, China.
Yudan SuState Key Laboratory of North China Crop Improvement and Regulation, College of Life and Science, Hebei Agricultural University, Baoding, China.
Jing RenState Key Laboratory of North China Crop Improvement and Regulation, College of Life and Science, Hebei Agricultural University, Baoding, China.
Fei YuState Key Laboratory of North China Crop Improvement and Regulation, College of Life and Science, Hebei Agricultural University, Baoding, China.
Lanying DuLindsley F. Kimball Research Institute, New York Blood Center, New York, New York.
Shibo JiangLindsley F. Kimball Research Institute, New York Blood Center, New York, New York.ORCID 0000-0001-8283-7135
Hebei Agricultural University · CNNew York Blood Center · USShanghai Medical College of Fudan University · CNZhejiang University · CN

Funding

Hebei Province's Program for Talents Returning from Studying Overseas CN201707National Natural Science Foundation of China 81601761National Natural Science Foundation of China 81974302Program for Youth Talent of Higher Learning Institutions of Hebei Province BJ2018045starting grant from Hebei Agricultural University YJ201843starting grant from Hebei Agricultural University ZD2016026
6 · The paper itself

Abstract

Respiratory tract viral infection caused by viruses or bacteria is one of the most common diseases in human worldwide, while those caused by emerging viruses, such as the novel coronavirus, 2019-nCoV that caused the pneumonia outbreak in Wuhan, China most recently, have posed great threats to global public health. Identification of the causative viral pathogens of respiratory tract viral infections is important to select an appropriate treatment, save people's lives, stop the epidemics, and avoid unnecessary use of antibiotics. Conventional diagnostic tests, such as the assays for rapid detection of antiviral antibodies or viral antigens, are widely used in many clinical laboratories. With the development of modern technologies, new diagnostic strategies, including multiplex nucleic acid amplification and microarray-based assays, are emerging. This review summarizes currently available and novel emerging diagnostic methods for the detection of common respiratory viruses, such as influenza virus, human respiratory syncytial virus, coronavirus, human adenovirus, and human rhinovirus. Multiplex assays for simultaneous detection of multiple respiratory viruses are also described. It is anticipated that such data will assist researchers and clinicians to develop appropriate diagnostic strategies for timely and effective detection of respiratory virus infections.

Indexed as

Clinical Laboratory TechniquesAdenovirus Infections, HumanCoronavirus InfectionsCOVID-19 TestingHumansImmunoassayImmunologic TestsInfluenza, HumanMultiplex Polymerase Chain ReactionNucleic Acid Amplification TechniquesPicornaviridae InfectionsReal-Time Polymerase Chain ReactionRespiratory Syncytial Virus InfectionsRespiratory Tract InfectionsRhinovirusVirusesadenoviruscoronavirusdiagnostic methodsinfluenza virusrespiratory syncytial virusrespiratory viral infectionrhinovirus

Identifiers

PMID31944312
PMCPMC7166954
OpenAlexW2999535351

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.